Drugs Reductio Ad Absurdum Of Abnormal Glucose Metabolism Metabolic Syndrome That Study

Purpose: Confirmed the anti-drugs and metabolic syndrome, abnormal glucose metabolism evidence-based classification of objectivity.Material and method: Clean Wistar rats with a total of 65, weight 180±20g, all male, from Liaoning University of Traditional Chinese Medicine Center for animal experiments. Standard rat food, Liaoning University of Traditional Chinese Medicine by the Experimental Animal Center. Model feed high fat diet, drinking water for 20% of the sucrose concentration in the water. To 65 rats to normal diet feeding adapteition in two weeks, using random number table 10 randomly selected as normal control group, the remaining model in rats given high-fat high-sugar diet that is high-salt diet and drinking water use 20% of the sugar water. Once every two weeks during feeding body weight and blood pressure measurement, a total of 12 weeks rats, fasting for 12 hours, collecting samples for testing targets . Model thirteenth week from the orbital venous blood of fasting rats. Rats were fed by gavage in rats after three weeks of intraorbital venous blood were determined in rats fasting blood glucose, blood lipids, blood prior to weighing. Selected standards in line with the rats into a mold, using randomized controlled randomly divided into nine groups, four of the experiment is responsible for type certification, together with the model group, a total of five groups of rats, namely: the model group (8), Group 1 (9) , on the 2nd group (9) , on the 3rd group (9) , on the 4th group (8). Corresponding respectively to give Liujunzi soup, Shenqi Dihuang soup, kidney soup, soup Xuefuzhuyu administered in accordance with the volume of rats (g / kg·d) = 6.25×x/60, x human dose. 8:00 on a one-time daily oral administration, the model group were given the same volume of distilled water and administered for 3 weeks, daily replacement of the first litter. SPSS10.0 detection through the indicators before and after analysis of variance and paired T test.Results:1. The first 12 weeks of the traditional Chinese medicine orally in rats with normal blood sugar control group were significantly different (P <0.01), with the model group, no significant difference (P> 0.05); by the traditional Chinese medicine administered 3 weeks after delivery (Article 15 weeks), the traditional Chinese medicine orally in rats with normal blood sugar control group were significantly different (P <0 . 01) , with the model group, no significant difference (P> 0.05); 12 Zhou rats for 15 weeks with blood glucose before and after the match T test, the groups were not significantly different (P> 0.05) .2. 12 weeks of the traditional Chinese medicine orally triglycerides in rats with normal control group were significantly different (P <0.01), with the model group, no significant difference (P> 0.05); 15 weeks of the traditional Chinese medicine orally Large TG mice and normal control group were significantly different (P <0.01) , compared with the model group, only Xuefuzhuyu Decoction group with which they have significant differences (P <0.01), the other group and model group, there was no significant difference (P> 0.05); 12 Zhou 15 weeks triglyceride of rats in each group before and after the match with T test: normal control group, model group, administered the traditional Chinese medicine group (except for soup Xuefuzhuyu group) were not significantly differences (P> 0.05) , soup Xuefuzhuyu triglyceride levels in rats for 12 weeks and 15 weeks compared are different (P <0.05).3 . 12 weeks of the traditional Chinese medicine orally high-density lipoprotein in rats with normal control group were significantly different (P <0.01), compared with the model group was no significant difference (P> 0.05); 15 weeks oral administration of the traditional Chinese medicine group high density lipoprotein in rats with normal control group were significantly different (P <0.01), compared with the model group was no significant difference (P> 0.05); with its own control before and after the pair T test in normal control group, model group and the oral administration of Chinese medicine group had no significance.4. 12 weeks of the traditional Chinese medicine administered insulin compared with normal control group are different compared with the model group was no significant difference (P> 0.05), model group and the difference between the normal control group (P<0 . 05) ; 15 weeks of the traditional Chinese medicine Prescription oral insulin levels and the difference between the normal control group (P <0.05) , 1 Recipe group on the 2nd and the 3rd party group to group and model group were significantly different (P <0.01) , 4 Recipe Group the difference between the model group (P <0.05), model group and normal control group were significantly different (P <0.01); with its own matching T test at 12 weeks and 15 weeks on the 2nd side group, side group on the 4th, the normal control group and model There was no difference in insulin rats (P> 0 . 05) , 1 Recipe group were significantly different (P <0.01), 3 Recipe their differences before and after the control (P <0.05).5.12 weeks of the traditional Chinese medicine group administered insulin sensitivity compared with normal control group were significantly different (P<0.01), compared with the model group was no significant difference (P> 0.05); 15 Weeks and 2 Recipe group, on the 3rd side group and on the 4th side group and the normal control group were significantly different (P <0.01), 1 Recipe group and the difference between the normal control group (P <0.05), 1 Recipe group to group on the 3rd model group were significantly different ( P <0.01), 2 Recipe group on the 4th side group and the difference between the model group (P <0.05); with paired T test on the 2nd side group on the 4th side group and the normal control group, no difference (P> 0.05) , side group on the 1st, the 3rd party group and the difference between the model group (P <0.05).6.12 weeks oral administration of the traditional Chinese medicine group weight, blood pressure and the normal control group were significantly different (P <0.01), with the model group, no significant difference (P> 0.05); 15 weeks oral administration of the traditional Chinese medicine and normal weight control group group were significantly different (P <0.01), with the model group, no significant difference (P> 0.05); own before and after the pair T test in each group for 12 weeks, 15 weeks no difference in body weight in rats.Conclusion:1. High-fat high-sugar, high-salt diet, and 20% of the sugar water to feed can be successfully produced and abnormal glucose metabolism in rat model of metabolic syndrome.2. Liujunzi soup, Shenqi Dihuang soup, kidney soup, soup, etc. Xuefuzhuyu traditional Chinese medicine can effectively improve the abnormal glucose metabolism and the metabolic syndrome of insulin levels.3. And abnormal glucose metabolism may be the existence of the metabolic syndrome spleen dampness, both Qi and Yin deficiency, yin and yang deficiency, blood stasis, such as context-based or card-type card folder and the existence of each other.