Study Of Aids, Herpes Zoster, The Medical Treatment Program

OBJECTIVES:A pragmatic clinical trials (PCT), designed to evaluate the effect of Chinese medicine in treating HIV-1(+) patients with herpes zoster (HZ). DESIGN AND METHODS:20 HIV-1(+) patients who had onset of HZ less than 7 days were registered in the study through the clinical department of Beijing DiTan hospital by following the 2004 AIDS Treatment Guideline(published by China Medical Association. The 20 patients enrolled in the study were randomly assigned into 2 groups of 10; the therapy group (G1) and the control group (G2). G1 were diagnosed with "Liver-Gallbladder damp heat" symptom subtype of HZ and were treated with Chinese herbal extract in conjunction with standard HZ medication (Valaciclovir); control group (G2) were receiving only Valaciclovir. The primary peremeter in this study are:the time of onset, the time of last vescile formation, the time of crust formation, and the duration of pain.The secondary parameter was the WHOQOL-100 form. The clinical data were loading into SPSS 17.0 for analysis. RESULTS:The ountcome of the treatment in both groups were assessed with the form prvided in appendix 2. G1 has shown 99.6% efficacy whereas G2 has shown 88.0% efficacy. CONCLUSION:G1 (Chinese medicine combine with standard medication) in treating HZ on HIV-1(+) patients shows statistically significant improvement (P<0.01) thanG2 (by using standard HZ medication alone).