Photodynamic Before And After The Treatment Of Port Wine Stains Laser Confocal Microscope Observation And Analysis

Objective:the study utilizes the confocal microscope to observe the efficacy of photodynamic therapy on port wine stainMethods:the 34 patients, clinically diagnosed with port wine stain by dermatologists, receive 2 photodynamic therapies. During first treatment, approximately one-fourth patients are assigned to the control group. There is no control group in the second treatment. All patients receive the confocal microscope examination before, immediately after,4 days after and 8 weeks after each treatment.Results:the mean vessel density and diameter of port wine stain lesion is statistically more than those of normal skin. In control group, there is no statistical difference in terms of the mean vessel density and diameter of port wine stain between 8 weeks after and before the first treatment. In the treatment group, the mean vessel density decrease significantly 8 weeks after the second treatment, but no statistical difference in terms of the mean vessel diameter between 8 weeks after the second treatment and that before the first treatment was observed. Conclusion:the confocal microscope is an effective and non-invasive technique to observe the efficacy of photodynamic therapy on port- wine stain.