The Design Calculations And Theoretical Study Of DNA Coding Sequences

The so-called DNA computing, mainly through the specific hybridization between the DNA molecules to completion. This process is formed by encoding the information for input DNA strings, and in vitro through biochemical reactions, this can be the solution from the reaction solution they need. Therefore, the encoding DNA computing research is the primary problem, it's good or bad will have a bearing on the success of DNA computing and DNA computing efficiency. For now, though a wide range of DNA computing model, but it does not have a code to meet the needs of different models, so very necessary with modern technology tools such as computer-aided biology software to achieve the maximum protection possible.Although the DNA encoding the calculation of the research has made some progress can be overcome to some extent the uncertainty in the biochemical reactions, to avoid false positive and false-negative solution may appear, but the depth and breadth of the study are still lacking in.In theory, the depth of the study, all of the individual constraints of the sector under the code still did not give a complete specific values, such as A4(n,d) etc.At a time when the value of n is small, you can get some yards of the exact value, but when the n value increases, the exact value of the rapid expansion of the range, allowing to determine the specific values difficult.The breadth of theoretical research, the current constraints on the combination of the boundaries of the code still remain in the majority of the next increase, even when the n value is small, we also did not give a specific amount but only give some rough Upper and lower bounds, and constraints on the combination of the code of the community not entirely theoretical studies, many combinations of the boundary conditions there is no in-depth study, for example A4(n,d)+A4RC (n,d)+ A4GC(n,d) etc., but these combined conditions, in practice it is to be taken into consideration.This article is based on the fully grasp the structure and properties of DNA molecules, DNA computing and mathematical mechanism of the biological mechanism, DNA computing operation of the design of biochemical experiments and the associated enzymes, fullly use the biological characteristics of DNA molecules for DNA coding sequence design problem is given Hamming distance, H the distance, Levenshtein distance and the combination of a combination of thermodynamic constraints under constraint community DNA coding theory and algorithms.