DNA Uptake Signal Sequence In The Evolution Of Pasteurellaceae And Neisseria

AS one of the main groups of biological, bacteria is the largest class species in nature. At present, many researchs have found that there were two kinds nutritional ways in bacteria, self-bacterial and heterotrophic, respectively. Almost all bacteria hold a kind of natural ability, in order to adapt to the surrounding environment, they uptake the DNA sequences from the other bacteria in environment, and merge these DNA into their genome. This is so called horizontal gene transfer.Horizontal gene transfer events should be related to the evolution of species. Many bacteria uptake the DNA seqences and transfer them as a part of theirself genome to adapt and survival from the surrounding environment. In bacteria, two types of bacteria, Neisseria and Pasteurellaceae families, have a visible character. When they uptake DNA sequences, a signal sequence can be observed in their genome. We call the signal sequence as the DNA uptake signal sequence (DUSS). For the Neisseria genus bacteria, their DUSS is a string with the length of 10, 5'-GCCGTCTGAA-3'. Again, for the Pasteurellaceae family bacteria, the DUSS is a short string with length of 9, 5'-AAGTGCGGT-3 '.In this paper, we study the fuction of DUSS in the evolution in two classes of bacteria based on the statistical analysis of the DUSS. Our interesting is mainly the distributive character of DUSS, such as the distribution of DUSS in the complete genome, coding regions and noncoding regions, respectively. For the coding regions, our focues is the frame site distribution of DUSS, and the hairpin structure for non-coding region. Based on the annalysis of DUSS in two classes bacteria, the DUSS-like sequence in other bacteria are find to understand the fuction of DUSS in the evolution of species.In the final part, a method of sequence comparison is suggestted to analyze the simlarities of sequences. Firstly, based on the S / S symmetric matrix, the numerical characterization of DNA sequences are obtained, and a 2-dimensional vector are constructed to describe the DNA sequence. The advantages of our method is its flexibility and extensive. Using the method, the 50S ribosome of Neisseria and Pasteurellaceae families are compared to exhibit the utility of the method.