| Objective:To investigate the role of Clusterin protein in male infertilityMethods:Immunohistochemical staining was used to detect the expression levels of Clusterin in 10 cases of normal testicular tissues,8 cases of obstructive infertility testicular tissues,13 cases of non-obstructive infertility testicular tissues. In addition, Western blot was applied to confirm the immunohistochemical staining results.Results:Immunohistochemistry coupled with Western blot demonstrated that the expression levels of Clusterin in testicular tissues with non-obstructive azoospermia remarkably decreased when compared to normal testicular tissues and testicular tissues with obstructive azoospermia.Conclusion:The reduction of Clusterin protein may play important role in non-obstructive infertility. |
PDF Full Text Request