| Background:Knee osteoarthritis, also known as osteoarthritis, degenerative arthritis, age-related arthritis. Is a common chronic joint disease.Longer duration of knee osteoarthritis, recurrent, the current poor treatment of western medicine, and side effects are more costly, which gave patients a tremendous spiritual and economic burden. Find an effective treatment became an urgent and important our current task.Plaster for external use so far all use the following problem:First, a considerable number of Chinese medicine formulations without external strapping clinical trials of new drugs; Second, even if a small number of topical drugs through clinical trials Plaster, both positive control The non-inferiority design, the choice of positive control problem (the choice of positive control, were not been placebo-controlled clinical studies, clinical trials of new drugs will not even), resulting in a lack of experimental basis for evaluating the effectiveness of drugs.In order to solve these problems, we placebo-controlled evaluation of their own pain and cold Plaster compound commonly used topical analgesic cream on Southern Star analgesic effects of knee osteoarthritis, knee osteoarthritis pain for the selection of external Plaster of therapy.Purpose:Compound analgesic cream by Southern Star for the analgesic effect of knee osteoarthritis studies for knee osteoarthritis pain topical use Plaster of therapy. Methods:Clinical observation methods used to select Traditional Chinese Medicine Hospital of Foshan City, orthopedic clinic treated patients met the inclusion criteria of the 20 patients assigned to the acrylic pressure-sensitive adhesive tape in the placebo group, the first use of the placebo compound 6, the Southern Star natural disasters pain 6 days. Application of VAS pain scores, analgesic effects before and after treatment and clinical efficacy.Results:6 days with the placebo group were using their own cream compound Southern Star 6 days VAS pain reduction rate, the difference was significant (P<0.01). Southern Star analgesic cream that compound to improve the joint pain has a significant effect. Placebo 6 days and self-control with pain relief cream compound Southern Star The clinical comparison of 6 days (P<0.05), statistically significant. Compound analgesic cream that Southern Star clinical treatment for knee osteoarthritis have a significant effect.Conclusion:These results indicate that:compound Southern Star analgesic cream on knee osteoarthritis pain better than placebo control group (P<0.05 or<0.01), and allergy is low, can be used as topical treatment of knee osteoarthritis pain Post Paste, and as a topical analgesic category Plaster drug clinical trials positive control. |