Re-evaluation Of Heart Function By Pulsed Tissue Doppler Imaging In Patients With Hypertension And Healthy Subjects

Objective To explore the PW-TDI for evaluating left ventricular function of normal and essential hypertension patients.Methods 43 patients with essential hypertension including 22 cases with hypertrophy and 21 cases with non-hypertrophy were selected. 65patients were randomly enrolled as normal control group. Measure myocardial motion peak velocity Vs,Ve, Va and calculate the Ve / Va ratio on valve annulus of left ventricular posterior septum ,lateral wall, right ventricular free wall, anterior wall,inferior wall,anterior septum and,posterior wall at standard long-axis view, 2-chamber view and 4-chamber view of left ventricular with TDI.Measure left ventricular ejection fraction (LVEF)with two-dimensional echocardiography,diastolic peak E, peak A on mitral valve with conventional pulsed Doppler ultrasound and calculate the E / A value.Results①Compared with controls,the systolic peak velocity on posterior septum,anterior septum,posterior wall,anterior wall,inferior wall of hypertensive patients were lower (P < 0.05) .②The diastolic peak velocity on posterior septum,anterior septum,posterior wall,anterior wall,inferior wall of hypertensive patients were lower than the controls .the diastolic E / A ratio and Ve / Va ratio on posterior septum,anterior septum,posterior wall,anterior wall,inferior wall were significantly lower than the controls (P < 0.05) .③The systolic and diastolic function betweenthe hypertrophy group and non-hypertrophy group have no significant change (P> 0.05).④peak speed of left ventricular lateral wall and right ventricular free wall have no significant statistical change (P> 0.05).⑤The systolic and diastolic amplitude of different sites have difference (P <0.05).Conclusion①Measured by pulsed tissue Doppler imaging in normal subjects in different parts of the valve annulus peak systolic velocity and Ve / Va ratio is inconsistent.②Compared with normal, hypertensive patients at different parts of the valve annulus peak systolic velocity and Ve / Va ratio reduction, but inconsistent in different parts of the lower level, suggesting that different parts of the heart wall is inconsistent with hypertension, the mechanism to be further study.