Preliminary Study Of Central Lung Cancer At 3.0T MRI

Objective:To investigate diagnosis value for differentiating central lung cancer from obstructive atelectasis and pneumonia.Methods:Thirty-five cases that had diagnosed to be central lung cancer with obstructive atelectasis by clinic and pathology underwent MRI scan at 3.0T MR. Contrast-enhanced CT examinations were done 28-30 seconds after injection of contrast agents at SIEMENS Sensation 16 CT. MRI scan sequences were as followed, T1WI, T2WI and DWI (b=400s/mm2). ADC and SI of central lung cancer and collapse lung tissues were measured and compared. The differentiation ability of T1WI, T2WI and DWI were compared.Results:Five cases could be distinguished on T1WI images, twenty-two on T2WI, twenty-seven on DWI, thirty on T2WI and DWI. The differentiation ability of T2WI was superior to that of T1WI. The differentiation ability of DWI was superior to that of T1WI, but there was no difference between DWI and T2WI. The differentiation ability of combining DWI with T2WI was better than that of T2WI single. The mean ADC value of central lung cancer (1.18±0.43)×10-3s/mm2 was significantly lower than that of collapse lung tissues (2.28±0.57)×10-3s/mm2 (P<0.05); The mean signal intensity of central lung cancer was higher than that of obstructive atelectasis and pneumonia on DWI images (P<0.05).Conclusion:3.0T MRI can be used to differentiate central lung cancer from obstructive lobar collapse. DWI is an effective complement of T2WI.