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Design And Implement Of Parallel Electrophoresis Chip Detection System

Posted on:2012-01-07Degree:MasterType:Thesis
Country:ChinaCandidate:W F DouFull Text:PDF
GTID:2218330368487858Subject:Microelectronics and Solid State Electronics
Abstract/Summary:PDF Full Text Request
Capillary electrophoresis chips are used in DNA sequencing, protein components research, drug screening, gene clinical diagnosis, etc; Multichannel capillary electrophoresis chip can also analysis of samples for testing, and they are more efficient, cheaper.Charge-coupled device (CCD) in the image sensor and non-contact measure-ment field of development is rapid, with low noise, wide spectrum response, precision and high sensitivity and reliability, etc.This paper builds a CCD (TCD1304AP) for photoelectric devices of multimodal capillary electrophoresis chip detection system, at the same time capillary electrophoresis channel flu-orescent signals are collected. Detection system light path part by part and circuit, light path part of simple structure, greatly simplifying the traditional complex light path structure; The circuit of the hardware circuit and software parts, hardware circuit including CCD circuit, the power circuit, voltage regulate circuit and data acquisition circuits, software part includes tim-ing driving module, USB chip firmware program module, USB drive modules and PC data acquisition program modules. System working principle for CCD fluorescent signals will be in-to analog signals, through the high speed A/D module into digital signals, then send the USB interface to the PC for real-time display.This paper introduces the design of the examination system, the light of the lens of diff-erent radius and the focusing more, its effect is evaluated, the optimization for the system to provide the basis; the results show that the system of the minimum detection limit, signal to noise ratio and repeatability detection system meets the design requirements, and has high ac-curacy, small size, high degree of automation, strong real-time property, etc.
Keywords/Search Tags:TCD1304AP, USB Port, Parallel Channel Detection
PDF Full Text Request
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