Effect Of Benzene On The Growth And Development Of Drosophila Melanogaster

Drosophila is an important model organisms have made outstanding contributions in the field of genetics, developmental biology, and neurobiology. It as a model organism, has a short life history, easy to feed, easily obtained, genome sequencing has been completed, with more use of research information and other advantages. Found when comparing Drosophila and human genome, the genes of the human body to cause human disease (including cancer-related genes) two-thirds can find similar genes in fruit flies. Currently, Drosophila has become an important model organism for genetic toxicology studies. Benzene as a chemical reagent in the industry, widely used in daily life. In the newly renovated home, benzene, often exceeding the phenomenon. Although studies have found that benzene can cause harm to the hematopoietic system of the human body and nervous system and reproductive and developmental systems, such as cause neutropenia, aplastic anemia and leukemia. However, the mechanism of benzene to produce toxic effects on the body has not yet been fully elucidated. This experiment benzene Drosophila growth and development, reproduction, life span, the antioxidant capacity of the study The results show that the speed of the medium containing2%and below the concentration of benzene in Drosophila development, the third instar larvae and adult weight did not significantly affect, no significant effect on the fecundity of fruit flies, but caused by the female, the maleDrosophila half ofthe time of death and all of the time of death was significantly reduced, a significant impact on the life of the fruit fly. Containing2%-benzene medium group, and benzene in the control group of Drosophila SOD activity and MDA Determination of benzene on the SOD activity of male flies, resulting in male fruit flies, SOD activity was significantly increased. Benzene medium also caused the SOD activity of the female fruit flies and female, the male fruit flies, MDA content increased, but statistics show that benzene group and the control group did not reach significant levels. Therefore, the experimental conditions, the oxidative damage caused by benzene on Drosophila may not result in Drosophila shortened life expectancy the only reason, there may be other ways lead to significantly shorten the life of fruit flies, the specific mechanism remains to be further explored. This study not only for the establishment of Drosophila as a model organism for detection of environmental contamination and toxicology to provide basic information, but also provide clues for further study of benzene on the mechanism of the organism influence.