Synthesis And Application Of Multi-step Conversion Of Carbonyl Of Aldehyde With Alkyne

The multistep conversion of C-H of carbonyl group of aldehyde with alkyne was studied and the application of the target molecule of a series of conversions was researched in detail for the UV-resin.Aromatic aldehydes were converted to the 1,3-dipole and then reacted with alkynes to synthesize isoxazole derivatives. Iron powder, ammonium chloride and the corresponding additives were used to selectively reduct the isoxazole compounds. Condition ptimization was made by selecting suitable solvent, reaction temperature and time to get the best condition for the reduction reaction. All the compounds synthesized were identified by a proton magnetic resonance spectroscopy, mass spectrometry and elemental analysis.The reducted products were epoxided to the multifunctional intermediates, which were then used as materials for Uv-resin after reaction with acrylic acid catalyzed by triphenylphosphine. The painting used in the field such as paper, furniture etc. was made from the Uv-resin,thinner and light-cure initiator。...