Preparation And Properties Of Anti-Biofouling Coating Based On PDMS/PMMA Diblock Copolymer

In recent years, the researches on anti-biofouling have preferentially focused on thosematerials which can cause microseparated surface, since these microseparated surfaces couldbe possible for inhibiting protein adsorption. Polysilicone has been widely used in weatherresistance, solution resistance, high and low temperature resistance, high hydrophobicityproperty and high air permeability property; Acrylate resin has many good properties, such asexcellent adhesive character, mechanical character, chemical stability,rich material and lowcost.In this paper, a series of poly(dimethylsiloxane)-block-poly((methyl methyacrylate)multiblock copolymers were synthesized using the macroazoinitiator containing PDMS asinitiator. The method used to synthesis the polydimethylsiloxane(PDMS)-basedmacroazoinitiator(MAI) was direct polycondensation of hydroxyalkyl-terminated PDMS with4,4’-azobis-4-cyanopentanoic acid(ACVA). Only one-step reaction was involved. Theresulted MAI had very high yield and initiation efficiency for initiating the polymerization ofmomomers.The surface properties of the resulted block copolylmers were characterized by thetechniques such as DSC, AFM and contact angle measurements. The DSC results showed thatcopolymers possessed the glass transition emperature of the PMMA and PDMS blocks; theresults of water-contact angle improved that the copolymer films was hydrophobic;Morphology of PDMS/PMMA copolymer thin films were analyzed by AFM measurementhad relationship with components, annealing at120℃, solvent types and spin-cast materials.The asymmetric copolymer thin films spin-cast from toluene on silicon presented anisland-like structure. The annealing process affected the surface morphology ofPDMS/PMMA copolymer thin films. The films could reach the complete thermodynamicequilibruim when the annealing temperature was higher than the PDMS glass transitiontemperature. The morphology of PDMS/PMMA copolymer thin films was different withsolvent to solvent. For thin films spin-cast makig of THF, the PMMA phase was pits inPDMS matrix. While the thin film spin-cast makig of toluene solution exhibited an island-likestructure.The microphase structures of the copolymer thin films were also strongly influencedby the different substrates. For an asymmetric block copolymer thin film, the PDMS and PMMA phases on mica substrate presented mesh-like structure parallelled to the film surface.All the copolymers with surface microphase separation had anti-biofouling properties,for the BSA protein adsorption experiment show that there is little BSA was adsorped by thediblock copolymers (about20-70μg),compared with the original BSA solution concentration,2mg/ml.