A Study Of Magnetite Nanoparticles Supported Salen Pd Complex As A Catalyst For Suzuki Reaction

The palladium-catalyzed coupling reaction has been shown as an efficient method for the construction of C-C bonds and plays an important role in pharmaceutical industry and organic synthesis. High activity for coupling reaction can be achieved using homogeneous palladium catalysts. However, many noble metals used in homogeneous system are quite expensive and it is difficult to separate the soluble catalyst from the reaction system. To address these problems, heterogenization of homogeneous catalyst is a promising option. The Fe3O4|nanoparticles are easily-prepared and surface functionalized and they can be recycled from the solution by external magnetic field. Hence, the catalyst supported on Fe3O4nanoparticles can be easily separated from the reaction system and reused. And Salen complex as a Schiff-type ligands. the ligand with palladium was found to act as efficient catalyst in coupling reactions.In this study, we described a methodology to immobilize Salen Pd (Ⅱ) complex on the surface of magnetite nanoparticles. The catalyst was characterized by ICP-AES. FT-IR, TE-M. XRD and VSM. The palladium catalyst exhibited efficient catalytic activity in coupling reactions with aryl iodides or bromides and phenylboronic acid at100°C for1-3hours under DMF7H2O. the yields were achieved over90%(except4-bromaniline). Furthermore, the catalyst could be magnetically isolated with a permanent magnet and have been reused in iodobenzene coupled with phenylboronic acid, the yields achieved above85%after reused at least5times.