Clinical Significance Of Elevated Plasma Fibrinogen And D-dimer Levels In Diagnosis And Treatment Of Pulmonary Embolism Recurrence

Objective To observe and evaluate clinical significance of plasmafibrinogen and D-dimer level in diagnosis and treatment of pulmonaryembolism recurrence.Methods77cases of remission in patients withinitial pulmonary embolism were divided into2groups:an initialtreatment group and a recurrence group.24cases of the recurrence groupwere divided into3groups:A group,B group,C group.To analysis whetherthere is a dominant difference plasma fibrinogen level,D-dimerlevel,gender, age between the initial treatment group and a recurrencegroup,to analysis the relationship between pulmonary embolism recurrenceand embolism stove distribution in patients.To compare the incidenceof pulmonary embolism recurrence and bleeding risk in A group,B groupand C group.Results Age difference was significant between the initialtreatment group and the recurrence group(P <0.05),gender was notsignificant(P＞0.05);There was no difference recurrence rate betweenA, B, C group(P＞0.05),bleeding risk raised(P＞0.05).There weresignificant differences in plasma fibrinogen level between the initialtreatment group and the recurrence group(P <0.05),the plasma fibrinogenand D-dimer level of the recurrence group is higher than the initialtreatment group(P <0.05),there is no significant correlation betweenpulmonary embolism recurrence and embolism stove distribution (P＞0.05).Conclusion The clinical significance of elevated plasmafibrinogen and D-dimer level in diagnosis and treatment of pulmonaryembolism recurrence was important,and predicted recurrence of pulmonary embolism.Plasma fibrinogen,D-dimer and age was important risk factorfor pulmonary embolism recurrence.continued anticoagulation treatmentnot decreased the incidence of pulmonary embolism recurrence,and bleedingrisk increased.