The Research Of The Value Of Microvolt T Wave Alternans (MTWA)To Forecast Complex Ventricular Arrhythmias In Non-ischemic Cardiomyopath Patient

Objective The number of sudden cardiac death in china increases every year,the main reason is ventricular tachycardia and ventricular fibrillation.According to the study,microvolt T wave alternans(MTWA) has close relationship to the occur of ventricular tachycardia and ventricular fibrillation.And it is recognized as the most predictive value for arrhythmic events non-invasive electrophysiological testing indicators.This study wants to discuss the value of microvolt T wave alternans to forecast complex ventricular arrhythmias in non-ischemic cardiomyopath patient.If we can find microvolt T wave alternans (MTWA) positive patient and early intervention,then the patient life is saved.Method60non-ischemic cardiomyopath patients were included,they were treated in liaocheng hospital during January2010to January2011.With MARS system produced by GE company in American to detect microvolt T wave in these non-ischemic cardiomyopath.According to the result,they were divided into two groups,30non-ischemic cardiomyopath patients with microvolt T wave alternans(MTWA)positive and30non-ischemic cardiomyopath patients with microvolt T wave alternans(MTWA) negative.30normal person were included in our hospital with ECG、chest X-ray and echocardiography were normal,they were regarded as control group.ECG monitoring was used and the stored data were analysised to see if complex ventricular arrhythmia happen.After these patients left hospital,we will follow-up for about One year,dynamic ECG were made to abserve if complex ventricular arrhythmia was happen. ECG monitoring was used and the stored data were analysised to see if complex ventricular arrhythmia happen.After these patients left hospital,we will follow-up for about One year,dynamic ECG were made to abserve if complex ventricular arrhythmia was happen. Result In60non-ischhmic cardiomyopath patients,the index such as heart rate、 cardiac function classification、left ventricular end diastolic internal clsaaics、ejection fraction compared to the normal control group have statistical significance.(p<0.05).And the index such as age、ion concentration in serum compared to the normal control group have no statistical significance.In MTWA positive group,malignant ventricular arrhythmia (include ventricular tachycardia、ventricular fibrillation and sudden cardiac death) were present in25patient. In MTWA negative group, malignant ventricular arrhythmia (include ventricular tachycardia、ventricular fibrillation and sudden cardiac death) were present in14patients.The two groups of difference there is significantly related(P<0.01)Conclusion T wave alternans positive has important value to predict serious ventricular arrhythmias in non-ischmic cardiomyopath patients.We must pay more attention to these patients.