Correlation Between~1H Imaging Spectroscopy And Diffusion Weighted In Prostate Cancer

Objective To evaluate the diagnostic value of DWI and MR body coil spectroscopic imaging in prostate cancer, and the seeking a more appropriate diagnostic criteria using3.0T MR. To evaluate the diagnostic correlation between proton magnetic resonance spectroscopy (3D1H MRS) and diffusion-weighted MR imaging (DWI).Materials and methodsSubjects: Sixty-five cases of patients with suspected prostate cancer on3.0T MR scanner, including conventional scan, DWI body coil imaging and spectroscopic imaging of prostate.Methods:In the case without the knowledge of the pathological results were observed for each subjects with bilateral peripheral zone and central zone each level ADC map and Cho+Cr/Ci metabolic maps. ADC map relatively low figure, select the region as the average ADC values in the region; and select a relatively normal ADC values of the region as a comparison. Cho+Cr/Ci select the relative metabolic meta bolic maps to calculate the effective hot zone voxel Cho+Cr/Ci values, the average value as the metabolism of high value; while selecting the corresponding non-metabolic hot spots calculated Cho+Cr/Ci value as a contrast. By histological evidence of ultrasound-guided puncture of the lateral lobe of the prostate for and found positive for adenocarcinoma of the side group and found no evidence of tumor side is negative.Statistical analysisAll data using SPSS16.0statistical software. Method of hypothesis testing through normal distribution of negative and positive test set of data distribution, respectively. If the data follow a normal distribution were compared using t test analysis of the positive areas and negative areas of the ADC plants, such as data do not obey the normal distribution, the use of Mann-Whitney U test. P<0.05considered significant difference Respectively negative and positive group Cho+Cr/Ci values using the t test mining. P<0.05considered significant differenceTo evaluate the diagnostic correlation between the (Cho+Cre)/Cit ratio and ADC values using Pearson correlation analysis. ResultsOn the GE3.0T MR when taking b=1500s/mm2, DWI imaging in differentiating benign prostate and prostate cancer that has good value in the diagnosis of prostate cancer patients with non-cancer patients were significantly different ADC values。Detection of the body as a living body metabolism level of noninvasive techniques,3.0T MR body coil for the application of MRS imaging is relatively simple and convenient, and the image quality is good. MRS helps to identify the peripheral zone of prostate cancer and benign prostate, the gland area also prompted the central lesion.Prostate Cancer and Non Cancer district cancerous area ADC values and Cho+Cre/Cit values、 cancerous area and Cho+Cre/Cit are negative correlated; ADC values of cancerous area and non-cancerous areas、Cho+Cre/Cit values of cancerous area and non-cancerous areas are positively correlated。...