| Background:Appendiceal abscess first described by Fitz in1886was one of the most common acute abdominal diseases in children. It was developed from acute appendicitis when the diagnosis and treatment was delayed. Appendiceal abscess formed due to the limitation the inflammation of appendicitis by greater omentum and the surrounding bowel parcel, or formation of localized peritonitis secondly to the appendiceal perforation or necrosis. The diagnosis of acute appendicitis in children especially infantile appendicitis was very difficult, because children couldn’t express pain exactly and would not like to be examined. The treatment was easy to delay, so that there was high incidence of appendiceal abscess in children. About4%-10%acute appendicitis developed appendiceal abscess in children. Appendiceal abscess could be diagnosed by B ultrasound, and the correct rate was more than90%. But the treatment has a difficult choose with operation or nonoperation. Some scholars believed that surgical removal of the appendix and abscess drainage the appendiceal abscess should performed early, which prevented the spread of inflammation and reduce the symptoms of systemic poisoning. However, operation for appendiceal abscess was more difficult. It may lead to inflammation diffused or accidental injury to surrounding structures, intestinal fistula, abdominal residual infection and other complications. Some scholars adopted celiac drainage,but ravaged treatment breeded complications of damnification in visceras. Other scholars have advocated conservative treatment. They believed that infants could confine and wrap the intra-abdominal inflammation, and anti-inflammatory treatment could dissipate the abscess. However, these inflammatory masses adhered surrounding tissue, and severely affected the blood circulation. It maked the antibiotics difficult to achieve effective concentration in the inflammatory masses, resulting ineffective in the antimicrobial therapy. Persisted painful abscess was subsisted after normal body temperature and normal blood test, so that the patient’s lives were seriously affected.Recent years, it has been reported that some Chinese medicine could improve the efficacy of appendiceal abscess treatment. Sargentgloryvine stem was a traditional Chinese herbal medicine. Sargentgloryvine Stem was traditional Chinese medicinal materials. Sargentgloryvine Stem has the functions of clearing away heat and toxic material. The investigation indicated that emodin and sitosterol were the central anti-inflammatory elements. Tannins was the the central chemistry ements of Sargentgloryvine Stem. Tannins has distinct capability to restrain bacterias epiphytes and microzymes. Tannins was the better capability to restrain Staphylococcus aureus. The effect was the correlation of content of total Ginsenoside and total Tannins and total Anthraquinone and total Chlorogenic acid. Sargentgloryvine Stem Antidotal Decoction was based on sargentgloryvine stem and supplemented with dandelion, the Patrina grass, tree peony bark, peony root, white peony root, fried hawthorn and raw licorice. It was extensive applied in the treatment of gynecological inflammation (e.g. pelvic inflammatory disease), gastrointestinal ulcers, gastrointestinal inflammation, chronic diarrhea and a variety of tumors.Hence we were trying to contraste the different effect of treat the appendiceal abscess in children between combine Sargentgloryvine Stem Antidotal Decoction with western medicine and western medicine only. Objective:The aim of this study was to investigate the clinical different effect of treat the appendiceal abscess in children. between combine Sargentgloryvine Stem Antidotal Decoction with western medicine and western medicine only.Methods:A total of100pediatric patients were randomly divided into experiment group and control group. The control group was administered with antibiotics alone. The experiment group was administered with antibiotics combination of traditional Chinese (Sargentgloryvine Stem Antidotal Decoction). The durations of symptom and sign disappeared, durations of hospitalization, white blood cells, C-response protein (CRP) and results of B ultrasound were compared between this two groups. SPSS17.0soft was used for the statistic analysis, P<0.05was considered as significant difference.Results:The durations of symptom and sign disappeared and the durationse of hospitalization in the experiment group were significantly shorter than these in the control group (P<0.05), the two groups have significant difference. The WBC and CRP at different time points detecting in the experiment group were significantly lowerer than that in the control group (P<0.05), the two groups have significant difference. The results of B ultrasound diagnosis at different time points in the experiment group were significantly smaller than that in the control group (P<0.05). The two groups have significant difference.Conclusion:Combine Sargentgloryvine Stem Antidotal Decoction with western medicine treatment on appendiceal abscess in children could obviously improve the therapeutic effect. |
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