The Different Ways Of Dialysis Affect Calcium And Phosphorus Metabolism After Renal Transplantation And Its Influencing Factors

Objective:We discuss whether the different ways of dialysis affect calcium and phosphorus metabolism after renal transplantation and its influencing factors.Methods:We observed serum calcium and phosphorus level in peritoneal dialysis group and hemodialysis group in the first3years after renal transplantation. Total number is71,40cases are peritoneal dialysis patients,31cases are hemodialysis dialysis patients. We recorded the serum calcium and phosphorus level, serum creatinine, eGFR before renal transplantation and after renal transplantation in the third month, the sixth month, the twelfth month, the eighteenth month, the twenty-fourth month, the thirtieth month and the thirty-sixth month. We compared the differences in the level of calcium and phosphorus between the two groups after renal transplantion and analyzed its influencing factors.Results:The serum phosphorus level in all time points after renal transplantion is lower than pre-transplantion, p<0.01. The serum calcium level in peritoneal dialysis group is higher than pre-transplantion, it is significant except the third month and the thirtieth month. The serum calcium level in hemodialysis group is higher than pre-transplantion numerically, but it is not significant. The serum calcium level between the two groups is not significant. The serum phosphorus level is higher in peritoneal dialysis group than in hemodialysis group in the sixth month. The incidence of hypercalciuria will decrease with time and hypophosphatemia will persist a long time after renal transplantion. The incident of hypophosphatemia in the first three years after renal transplantion is6-17%. Hypercalciuria after renal transplantion is associated with pre-transplant calcium level in the third month, the sixth month, the twelfth month, the thirtieth month, and is associated with post-transplant creatinine level in the third month, and is associated with dialysis time in the sixth month, the twenty-fourth month, the thirtieth month. Hypophosphatemia after renal transplantion is associated with dialysis time in the third month, the eighteenth month and is associated with the different ways of dialysis in the thirty-sixth month.Conclusion:We observed common hypercalciuria and hypophosphatemia after renal transplant patients. The incidence of hypercalciuria will decrease with time and hypophosphatemia may last a long time after renal transplantion. The incident of hypophosphatemia in the first three years after renal transplantion is6-17%. The different ways of dialysis do not affect calcium metabolism after renal transplantation. The different ways of dialysis have little effect on hypophosphatemia. Hypercalciuria after renal transplantion is associated with pre-transplant calcium level, post-transplant creatinine level, dialysis time. Hypophosphatemia after renal transplantion is associated with dialysis time.