Analysis On Epidemiology And Clinical Manifestations Of Influenza A(HINI) In Guangxi

OBJECTIVES:The epidemiological and clinical features of A(H1N1) influenza cases in Guangxi in2009were analyzed to provide the reference for treatment and prevention of H1N1.METHODS:The clinical data of122hospitalized cases with H1N1in eight different hospitals from August2009to January2010in Guangxi were collected and retrospectively analyzed in epidemiology, clinical features and laboratory test.RESULTS:This outbreak of H1N1occurred and achieved peak in November to December,2009. the most cases were local cases,2cases were imported, Ratio of male and female was1.5to1,86.9%of cases were10to25years old and average age was (18.2±9.6) years old,86.9%of cases were students. The ratio of ethnic Han to Zhuang was1.03:1. The main clinical manifestations were fever, cough, thoracalgia, no specific feature was seen. WBC was found normal or reduced, accounted for91.0%.13.5%of cases had hypokalemia. Aspartate aminotransferase (AST) was increased, accounted for14.8%, alanine aminotransferase(ALT) was increased, accounted for8.2%, and creatine kinase (CK) was found abnormal, accounted for37.6%. Pneumonia was the most common in imaging examination.70of cases(57.4%) accepted antiviral therapy,120patients were rehabilitated, discharged and2patients died.CONCLUSIONS:H1N1reached the peak in winter. The crowd were teenagers, the most cases were students. Clinical manifestations had no specials; WBC was found normal or reduced; Pneumonia was the most common manifestation in imaging examination. The most cases had mild symptoms, but in severe cases there was a higher mortality.