| Objective:Analysis the clinical and pathologic data of stage I-IIB cervical adenocarcinoma and assess the prognostic factors in this patients.Methods:One hundred and three cases of I-IIB primary cervical adenocarcinoma who diagnosed and underwent surgery in Zhejiang University Women’s Hospital between1999.10and2010.6.The clinical and pathologic data were reviewed retrospectively. And the prospective factors were explored by univariate and multivariate analysis.Results:The5-years overall survival rate and the5-years recurrence-free survival rate were82.3%,81.3%, respectively. In univariate survival analysis, age<40years, the biggest line of tumor, resection margin, lymph-vascular space invasion (LVSI), lymph node metastasis and parametrial involvement were significant factors for overall survival(P<0.05), and the biggest line of tumor, resection margin, lymph-vascular space invasion, lymph node metastasis and parametrial involvement were significant for recurrence-free survival (P<0.05), respectively. But, using multivariate analysis, only lymph node metastasis, resection margin remained significant independent predictors for overall survival and recurrence-free survival (P<0.05), and the biggest line of tumor was significant independent predictor for recurrence-free survival (P<0.05)Conclusions:The retrospective study suggests that lymph node metastasis, resection margin are independent factors in prediction of survival in cervical adenocarcinoma, and the biggest line of tumor is independent predictor for recurrence-free survival of cervical adenocarcinoma. |
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