Differentiation Of Benign And Malignant Pancreatic Endocrine Tumors With CT、MR

Objective:To investigate the imaging characteristics of pancreatic endocrine tumors (PET) and evaluate CT and MR in diagnosis and differentiation of PET.Methods:Imaging features of43patients with histopathologically proved PET (18well differentiated endocrine tumors,24well differentiated endocrine carcinoma and1poorly differentiated endocrine carcinoma) were analyzed retrospectively. Thirteen patients had both CT and MR scans,28patients had CT only and two patients had MR only. The involved data was analyzed using statistics software of SPSS19.0.Results:There was a statistical difference on diameter between benign and malignant lesions. Of the20benign lesions, two insulinoma were missed by CT, but detected by MR. Post contrast enhancement, well-defined lesions showed homogeneous enhancement compared to the pancreatic parenchyma on both CT and MR. Of the32malignant lesions, after contrast media injection, ill-defined lesions showed heterogeneous enhancement.Calcification(7).cystic degeneration(3).hepatic metastases (16), splenic metastases(3), gastral metastases(2). adrenal metastases(1), venous invasion(14), lymphadenopathy(7) were demonstrated on imaging.Conclusion:CT and MR are very usefull in differentiation of benign and malignant PET. There were some marked differences on radiological feature between benign and malignant lesions.