Impact Of Cesarean Section Delivery On Gut Intestinal Bifidobacteria And Lactobacillius In Newborn Babies In The First Three Days After Delivery

Objective： This study was designed to investigate the effect ofcesarean section delivery on the development of gut microflora in neonatesin the first3days of life.Methods：Eighty tree cases of healthy formula-fed term infants wereenrolled in the study and divided into two group: vaginal deliverygroup(n=39) and cesarean section delivery group(n=43). The faecalbifidobacteria and lactobacillius of neonates were consecutively quantifiedby real-time polymerse chain assays during the first3days after birth.Results：Bifidobacteria logarithmic absolute value（lg copies/g）of thefirst three days after birth were5.65±0.64，6.36±1.00，6.69±1.06incesarean section group respectively and5.66±0.75，7.19±1.15，7.49±1.29in vaginal delivery group. Lactobacillius logarithmic absolute value（lgcopies/g） of the first three days after birth were4.66±0.73，4.71±0.84，5.16±0.55in cesarean section group respectively and5.88±0.41，6.30±0.99，5.79±0.33in vaginal delivery group.The above value hadstatistical difference between group to group in different time (p＜0.005). Conclusions： Cesarean section decrease significantly the count ofprimary intestinal bifidobacteria and lactobacillius in formula-fed terminfants.