Combined Selective Portal Venous Occlusion And Regional Hepatic Artery Occlusion In Hepatectomy Of Hepatocellular Carcinoma

Objective：To evaluate the therapeutic effect of hepatectomy under selective portal venousocclusion and regional hepatic artery occlusion for hepatocellular carcinoma. Providea new option for hepatic inflow occlusion in hepatectomy.Methods：Retrospective analysis of clinical data of the hepatocellular carcinoma patientswho under the hepatectomy in Hepatobiliary Surgery of our hospital from July2007to June2010. According to the hepatic vascular occlusion methods, the caseswho meet the selection criteria were divided into three groups (group A, group B andgroup C). Forty-eight cases of hepatocellular carcinoma received the novel therapy(group A).The result were compared with that of seventy cases treated by routine liverresection (group B and C). Analysis of the general situation of the three groups werecompared in patients with tumor-related conditions, intraoperative (operative time,blood loss) and postoperative (indicators of liver function recovery and postopera-tive hospital stay) indicators.Results：1.In general situation: three groups of patients, age distribution, sex ratio,whether the hepatitis B virus infection, with or without cirrhosis of the liver showedno significant difference.2. Tumor-related conditions: tumor size, with or without satellite nodules,portal vein violations were no significant differences.3. Intraoperative situation: The operation time in group A than in group C isshort, the group A and group B was no significant difference; Group A of theintraoperative blood loss was less than in group C, group A and group B the differ-ence was not statistically significant.4. Postoperative situation: Three group had no deaths, postoperative liverfunction recovery in group A than group B fast, group A and group C was no significant difference; recovery of gastrointestinal function in group A than in groupB short, group A and group C was no significant difference; postoperative hospitalstay is shorter than in group B, group A and group C was no significant difference.Conclusion：Hepatectomy under selective portal venous occlusion and regional hepatic arteryocclusion is safe and effective, and it is more suitable for the hepatocellularcarcinoma patients with operative indication than routine1iver resection.