Clinical Study Of Mannitol Combined Ileus Tube To Treat Adhesive Intestinal Obstruction

Objective Adhesive intestinal obstruction treatment achieved good decompressioneffect by ileus tube. This study aim to explore the effects of mannitol on adhesiveintestinal obstruction by ileus tube.Methods50adhesive intestinal obstruction patients we selected from December2009to December2011which randomly divided into control group(N=27) and experimentalgroup(N=23). All patients have abdominal surgery history and the strangulatingintestinal obstruction were exclusion. All Patients were treated with routine therapyincluding fasting, nutritional support, maintaining electrolyte and acid-base balance,usage antibiotics, while Patients of experimental group received mannitol based onroutine therapy. Patients in the control group injected with paraffin oil. To compared allpatients in degree of remission with abdominal distension, abdominal pain, anus restoreto exhaust time, the degree of abdominal circumference decreases, the first24hoursdrainage, gas-liquid plane disappeared, operation rate and average length of stay.Analysis the clinical efficacy of mannitol on adhesive intestinal obstruction by ileustube, explore the combined use of clinical value.Results24cases in treatment group were cure or alleviated, while one patients withileocecal tumor increased abdominal pain and bloating after using mannitol.2patientswith simple adhesive had surgical intervention.15cases in the control group cure oralleviated. while8patients with simple adhesive had surgical intervention. Theexperimental group and control group have significant differences on recovery of flatusand stool [88.9%and35.7±2.3h vs65.2%and43.7±4.1h](P<0.05), degree of abdominal circumference [15.0±1.5cm vs13.0±1.4cm](P<0.05), the first24hours of digestivejuice drainage [1604±364ml vs585±126ml](P<0.05), the disappearing time ofgas-liquid and hospitalization time is shorter than the control group [43.3±8.5h and9.0±1.4d vs55.0±10.1h and12.5±2.0d](P<0.05), the rate of transferring to operation inexperimental group (11.1%) was significant lower than that in the controlgroup(34.8%).Conclusion Using mannitol by ileus tube plus routine treatment is an effectivemethod to treat adhesive intestinal obstruction by significantly improving clinicalsymptoms, thus improving the decompression drainage, increasing non-surgical curerate, decreasing the rate of transferring to operation and shortening hospital stay. Theresults of study can provide a new method for the treatment of adhesive intestinalobstruction.