Left Ventricular Longitudinal Function In Pregnancy Induced Hypertension Syndrome Assessed By Velocity Vector Imaging

Objectives:Recently, some researches assessed the systolic and diastolic function of left ventricle in Patients with Pregnancy-induced Hypertension are scared. It is obscure whether or not left ventricular dysfunction exists in patients with Pregnancy-induced Hypertension(PIH).Velocity vector imaging(VVI) is a novel technique which can non-invasively detect regional myocardial function.VVI is can reflect subtle functional changes of regional myocardium and widely used to detect cardiac function.The purpose of this study is to assess the left ventricular Function in patients with Pregnancy-induced Hypertension Using VVI,to observe the regularity of long axis left Ventricular,to discuss the important value of velocity vector imaging in quantitatively evaluating regional Longitudinal systolic and diastolic function of left ventricle.Subjects and Methods:82patients with Pregnancy-Induced Hypertension(PIH) and33normal pregnant controls (NP) are included.All patients were divided into three groups:patients with Gestational hypertension(GH)25cases,patients with mild preeclampsia(M-PE)27cases,and patients with severe preeclampsia(S-PE)30cases.They were matched with for age、 pregnancy weeks. Exclusion criteria for all subjects were cardiac valve disease、congenital heart disease、Diabetes mellitus、thyroid disease、 metabolic disease、connective tissue disease、dystrophy、severe dysfunction of liver and kidney.left Ventricular diameter (LVD)、left Atria diameter(LAS)、Interventricular septum thickness(IVST). posterior wall thickness(PWI)、ejection fraction(EF)、fraction shortening (FS) mitral early diastolic peak flow velocity(E)、late diastolic peak flow velocity(A)、E/A ratio、systolic max velocity(SVmax)、systolic max strain (SSmax)、systolic max strain rate(SSRmax)、diastolic max velocity(DVmax)、diastolic max strain(DSmax)、diastolic max strain rate(DSRmax) are recorded.Results:All the Vmax、Smax and SRmax at prophase of diastole and the Vmax、SRmax at advanced stage of diastole were obvious lower in patients with Pregnancy-Induced Hypertension. All the Vmax、Smax and SRmax at prophase of diastole and the Vmax、SRmax at advanced stage of diastole were obvious lower in Mide preeclampsia and Severe preeclampsia which were compared with gestation hypertension. All the Vmax、Smax and SRmax at prophase of diastole and the Vmax、SRmax at advanced stage of diastole were obvious lower in Severe preeclampsia which were compared with Mide preeclampsia. All the Vmax、Smax and SRmax at systole period were obvious lower in Mide preeclampsia and Severe preeclampsia which were compared with normal pregnant women. All the Vmax、Smax and SRmax at systole period were obvious lower in Severe preeclampsia which were compared with gestation hypertension. Conclusion:The regional relaxation were obvious decrease in Pregnancy-Induced Hypertension than Normal group.Moreover, the regional contraction were obvious decrease in Mide preeclampsia and Severe preeclampsia than Normal group.And there were not segmental differences.The parameters change trends were similar with Normal in Pregnancy-Induced Hypertension. Using VVI could objectively and sensitively detect subtle changes of left ventricular systolic and diastolic function in patients with Pregnancy-Induced Hypertension.Therefore VVI could be a useful tool in assessing the myocardial regional function.