| AIDS, acquired immunodeficiency syndrome is a cause of human infection with the human immunodeficiency virus infected immune function, partial or complete loss, while syndrome complicated by a series of opportunistic infections and tumors, which clinical manifestations in various forms, but with the advent of antiviral therapy, AIDS has changed from a fatal disease to a controllable chronic disease.According to the China CDC estimates that as of the end of2011, HIV carriers and AIDS patients the survival of our country is about780,000, the annual new infections by48,000deaths28000. The epidemic has covered all provinces, autonomous regions and municipalities. China is currently facing the peak period of AIDS morbidity and mortality, have been drug addicts, prostitutes and other high-risk groups to the general population. Although AIDS has been transformed into a controllable chronic disease, antiviral therapy is expensive, and more side effects. In contrast, Chinese medicine has its unique theoretical and clinical advantages. Beginning in the1990s, the state of clinical practice and research of Chinese medicine treatment of AIDS, has achieved some results, to commence with the Chinese medicine to participate in AIDS treatment research in-depth, will benefit an increasing number of AIDS patients.Under the guidance of the overall concept of traditional Chinese medicine diagnosis and treatment principles of Chinese medicine treatment of AIDS, having made some progress. However, due to AIDS Chinese medicine treatment of the theory of a late start, especially the climate research of TCM AIDS, there are more, generally stay in the simple empirical summary level, the lack of systematic, large-scale clinical epidemiological study, so AIDS in a large sample of traditional Chinese medicine syndrome is particularly necessary.This study is part of the major projects of national science and technology "AIDS Chinese medicine syndrome," the first part of the literature study, a retrospective study of phonological aspects of the literature on AIDS-related permit to carry out a simple comb. The second part of the statistical analysis and mining of AIDS four diagnostic information, check against climate effects of traditional Chinese medicine syndrome of AIDS and the clinical factors described from different angles.1Research Purposes607cases of blood collection and supply transmission of HIV/AIDS infected persons, with the four diagnostic information collection, the collation of the four diagnostic information, analysis and statistics, to explore by the blood collection spread of HIV/AIDS infected persons TCM Syndrome characteristics.2Subjects607cases of HIV/AIDS infected persons from Henan, Anhui regional cooperation hospital screening of the population, met the diagnostic inclusion criteria.3ResearchDeveloped by the major projects of the State AIDS TCM Syndrome "AIDS Chinese medicine syndrome four diagnostic information collection table with the four diagnostic information collection transmitted infections through blood collection and supply, including general information, nearly three months symptoms and signs, treatment, drug use, the tongue and pulse, and laboratory test data.4Research MethodsSPSS17.0software package for statistical processing and analysis. Respectively, using the descriptive analysis, exploratory factor analysis and chi-square test.5Results5.1The literature studyAccording to the literature search strategy will retrieve the manual screening and Literature Classification, retrieved a total of nearly more than500Chinese medicine research literature related to AIDS, pick out the57card type to meet the requirements of the relevant literature for analysis. Related to AIDS, traditional Chinese medicine syndrome in the literature concerning a relatively small, and each article of TCM clinical dialectical different ways, there are viscera dialectical, sanjiao syndrome differentiation, and eight principal syndromes. Concern in the literature similar symptoms, mainly fatigue, rash, fever, cough, poor appetite, diarrhea, chest tightness, spontaneous perspiration, headache, weight loss, swollen lymph nodes, night sweats, nausea, hair loss, dry mouth, etc. Evidence of the asymptomatic period. damp-Heat syndrome, the Qi stagnation and phlegm coagulation, deficiency of both QI and YIN, AIDS in of damp-Heat syndrome, phlegm-heat accumulated in the lung, phlegm and blood stasis.5.2607cases of blood collection and supply-the spread of HIV/AIDS infection by the TCM Syndrome research5.2.1.607cases of infection by the AIDS Syndrome of the overall distribution lawInternal deficiency of QI detection rate information of all607cases of infection visits and found that involving the Yin and Yang, both Qi stagnation, blood deficiency; external evil susceptibility of view, the first wet evil, then the fire (heat) evil, cold pathogen; disease mainly in the kidney involving the spleen, lung and liver, and the inside card-based, tongue color pink tongue, followed by red and pale tongue; tongue-shaped common fat big scalloped see, followed by thin thin and cracks; tongue color with white fur is the most common, followed by yellow moss; moss quality thin coating, followed by to see the thick greasy fur; pulse the most common veinlets, followed by a deep pulse, rapid pulse.607cases of infection were the most common symptoms are weakness, fatigue, and shortness of breath, palpitations, irritability and other symptoms. Various organs are involved; the performance of the disease is more complex. As can be seen are the similarities and differences in the symptoms of the clinical results of the survey and literature research, this study of607cases of AIDS transmission routes a single blood collection were infected with their own physical, environmental and social factors, symptoms, the performance of the disease naturally has its own characteristics. After appropriate evidence-based norms and merge,607cases of infection of Clinical Investigation found that there were nearly more than50kinds of Yang deficiency of spleen and kidney, Qi and Yin deficiency, deficiency of spleen-qi syndrome type. The overall the dialectical impression to the main deficiency, both false is mixed. The combination of factor analysis results by the fourth power of the orthogonal rotation and gravel map, extract the first five factors the main common factor. There were Damp heat factor, inverse gas factor, virtual blood and Qi factor, Qi deficiency factors and emotional factors. Involving the organs involved in the renal liver, spleen, lung, heart.5.2.2. Disease located in the immune indicators of sexually transmitted diseases, interventions, clinical stage, and explore gender differencesDisease resistance in male and female, different means of intervention and no significant difference after the first visit data analysis, but different clinical stages and CD4levels have significant differences.607cases infected with the disease in TCM bit in the performance of gender, there was no significant difference. The intervention of different treatment options, there are differences, but the difference was not significant different clinical stages and CD4levels have significant differences.5.2.3. Disease, disease symptoms and syndrome type and clinical stage, immune indicatorsAIDS infected with the pathogenic Yang deficiency is internal and both Yin, Qi. Dampness, fire (heat) the susceptibility of evil; Condition mainly involving organs as the kidney, spleen, lungs; AIDS infections, the main symptoms are weakness, fatigue, a small increase and shortness of breath,21≥50%frequency of symptoms; AIDS infected syndrome type performance Yang deficiency of spleen and kidney, Lung and spleen-qi deficiency and Qi and Yin deficiency.Asymptomatic infections disease for internal were Qi deficiency, both Yang and Yin. Dampness, fire (heat) the susceptibility of evil; Condition involving the spleen, kidney, liver and viscera; asymptomatic phase of infection by the main symptoms are weakness, fatigue, waist and knee pain and dizziness, the frequency of≥50%of the symptoms4; asymptomatic phase of infection by card type were spleen-qi deficiency, dampness and heat in spleen and Yang deficiency of spleen and kidney.CD4<100infections were diseased to deficiency of Qi and Yang-based. Fire (heat) the susceptibility of the evil and wet evil; disease mainly involving organs as the kidney, spleen, lung; clinical manifestations were fatigue, forgetfulness, waist and knee pain and nocturia increased mainly.,20≥50%frequency of symptoms; symptom syndrome mainly as Yang deficiency of spleen and kidney, Lung and spleen-qi deficiency and spleen-qi deficiency.100<CD4<200group infected with the pathogenic were Yin deficiency based, both Yin and Yang deficiency. Dampness and fire (heat) evil susceptibility. The disease mainly involved the organ for the spleen, lung, and kidney. The clinical manifestations of weakness, fatigue, irritability, shortness of breath mainly. There were23≥50%frequency of symptoms; symptom syndrome mainly as Qi and Yin deficiency, lung and spleen-qi deficiency and intense liver fire pattern.201<CD4<350infected with the disease to Qi deficiency both Yin and Yang deficiency. Dampness and fire (heat) evil susceptibility; condition mainly involving the organ for the spleen, liver, kidney; clinical symptoms as fatigue, irritability, waist and knee pain, and forgetfulness.22≥50%frequency of symptoms; symptom syndrome mainly as Yin deficiency of liver and kidney, intense liver fire pattern and Yang deficiency of spleen and kidney.351<CD4<500infected people in disease resistance to deficiency of Qi, Yin and air stagnation, dampness and fire (heat) evil susceptibility; disease involving multi-organ as the kidney, spleen, liver., symptoms of pain, symptoms of lassitude, fatigue, irritability and forgetfulness mainly.13≥50%frequency of symptoms; symptom syndrome mainly as Qi and Yin deficiency, Yang deficiency of spleen and kidney, syndrome of liver depression and spleen deficiency.CD4>500infected persons pathogenic Qi deficiency, Yin deficiency-based, both Yang and Qi stagnation. Dampness and fire (heat) evil susceptibility; mainly involving organs as the kidney, liver, lung, where the majority of permit symptoms of fatigue, waist and knee pain, nocturia, and a cold-based.21≥50%frequency of symptoms; symptom syndrome mainly as Qi and Yin deficiency, intense liver fire pattern and deficiency of lung-qi.5.2.4DiscussionAIDS not a simple disease but by a combination of a variety of related diseases constitute one class syndrome. Although the climate of understanding of the Chinese medicine profession for AIDS syndrome can not be unified, but it is also a matter of opinion. Through field research, the systems are considered, the HIV infection early existence of the incubation period showing the Incubated temperature characteristics of the disease, the dialectical should comply with the Incubated temperature syndrome differentiation characteristics; The lingering illness of AIDS in the mid-refractory presents the characteristics of the wet temperature, the dialectic of course, should comply with the wet temperature characteristics identified; advanced AIDS because of chronic illness into the dirty, while showing the characteristics of consumptive disease, Syndrome from the organs of internal injuries identification method.The information collected in this study are mostly AIDS patients, chronic illness into the dirty, is a consumptive disease areas, so this study from the perspective of syndrome differentiation of syndrome divided. Summarized607cases by the blood collection spread of AIDS patients, and found that the main symptoms of weakness, fatigue, shortness of breath, palpitations, irritability; from the TCM, involving multiple organs, the performance is more complex; and symptoms with the literature results some difference. Dampness in patients with the most common cause of disease study of AIDS patients found that, I speculated that this may be a lingering illness, diseases, and acquired spleen and kidney of gas impairment. Is Evils infection with the human straight in the lung and stomach, a long time damage the spleen and kidney, unlike other diseases, the damage process is slower, the course of time involving the internal organs of the body. Therefore, I more inclined to the HIV virus as the TCM Dampness In addition to the performance of syndrome, AIDS medicine treatment methods is also very similar to the treatment of wet evil, such as the Dampness easy to damage the body’s yang, the easy passage of the body under the coke longer duration, touching, etc., consistent with AIDS and many other features.Main syndromes observed in patients with deficiency-based, this may be the condition in which the clinical stage, the statistics showed that84.02%patients were of AIDS patients, fewer patients with asymptomatic stage, and the patients living conditions and medical the environment is relatively poor, the results can basically reflect the blood collection spread of HIV/AIDS infected persons, especially AIDS of TCM syndromes. Check against climate, clinical stage and the in-depth study of the immune parameters found with the further deterioration of the condition, the continuous decline in CD4counts, disease is also the main main change to Yang Qi deficiency, yin deficiency process, disease location, finally showed the main changes in the process of kidney and spleen Yang of the pathological process of various organs and folders. This study of607cases of AIDS patients, both blood collection and supply infection, a single route of transmission, by his own physical condition, living environment and socio-cultural factors influence their symptoms and disease manifestations naturally has its own characteristics.The research related to ethical issues, and some have been taking antiviral therapy, is unable to collect the information of the natural course of AIDS, and collected information by the time limit restrictions, may not fully reflect the AIDS full disease syndrome characteristics, subject to further track investigation. On the other hand, before and after the interventions are used, the patients in the absence of information, you can not compare and evaluate the pros and cons of the interventions, pending information collection more stringent control and norms. |
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