Sexual Function Research In Taking Methadon Patients, Drug Users And The General Population In Urumqi In Uygur

Objectives: To investigate the sexual function of heroin dependent patients afterMethadone maintenance treatment, discuss the potential harmfulness of Methadone to thesexual function of the drug addicts, analyze the causes and provide a solution. Methods:Use “Self-made questionnaire”,”questionnaire on the affect of erectile dysfunction to thequality of life” and “The International Index of Erectile Function”(IIEF–5) survey and131Uyghur male patients received treatment by6months from7ambulatories in Urumqiand129Uyghur male patients arrested in not more than a month from Compulsoryaddiction treatment centre as study group and130male residents from four communitiesin Urumqi as control group, carry on face to face questionnaire to compare the sexualfunction of each group. Investigate the influence factor of the erectile dysfunction of malepatients using single factor analysis and Binary Logistic Regression analysis. Results:Single factor analysis represents that there are statistical differences（P＜0.001） betweenthe three groups in sexual desire, erectile maintenance time, premature ejaculation, thenumber of nearly three months of sexual behavior, sex satisfaction, Index of erectilefunction, in the influence degree of erectile dysfunction to the quality of life and so on.Binary Logistic Regression Analysis. represents that the general population as a reference,there are statistically significant differences compared to MMT group and drug takinggroup in sexual function(OR=17.340, P＜0.001）,（OR=6.964, P＜0.001）. The differencewas not statistically significant between MMT group and drug taking group in sexualfunction（OR=0.402, P=0.075）. The factors that affect sexual function are: the age andprostatitis. As compared to the20～29y male There are statistically significant differences in30～39y male group and≥40y male group in sexual function （OR=2.506,1.218~5.158）,（OR=2.763,1.016~7.519）. Prostatitis（OR=2.257,1.021~4.993）.Conclusion: Heroin can cause male sexual dysfunction. Methadone is not the reason inreducing sexual function, but large doses of methadone maintenance treatment influencethe MMT patients’ sexual function at certain extent. Low maintenance of dose canimprove the sexual function. So correctly adjusting the maintenance dose will effectivelyimprove the sexual function of the patients.