The Analysis Of Pathological Features And Prognosis For Adenocarcinoma Of The Esophagogastric Junction

Objective: This study aims to explore the clinical and pathological features ofthe Adenocarcinoma of the esophagogastric junetion、the surgical treatment ofabdominal transhiatal approach and the factors affecting prognosis.Methods: Retrospectively analyze the clinical data of218AEG cases fromJanuary2010to January2012treated in the First Hospital of Jilin University,divided according to the Siewert classification criteria, comparing age, gender,TNM stage, histological grade, lymph node-positive rate, positive margin rate,postoperative complications of different Siewert subtypes, comparingsurgery,lymphadenectomy situation of different cases, comparing free survivalof radical mastectomy.Results: There are145cases (66.5%) Siewert II, and73cases (33.5%) SiewertIII in the whole218cases. There is no distinctive in Age and sex ratio betweentwo groups. Compared with typeⅡ, TypeⅢ is more prone to the stomach walldeep infiltration and perigastric lymph node metastasis, so typeⅢ is later thantypeⅡaccording to TNM stage. The degree of differentiation for G3/4patientsthe proportion was significantly higher in the type Ⅲ than typeⅡ,Vesselinvasion positive rate was significantly higher in the type Ⅲ than typeⅡ.Withthe surgical treatment of abdominal transhiatal approach, Open and laparoscopic-assisted therapy can achieve the same curative effect. Palliativeresection AEG significantly affectting1-year survival rate of the patients. Theimpact of radical resection the AEG in patients with1-year survival factorsincluding tumor TNM stage, tumor histological grade, vascular invasion andage, and sex of the patient, the surgical approach was no significant correlation.Conclusion:1.Type II and type III AEG have different clinicopathological features in the Tstage, N stage, TNM stage, histological grade, and vascular invasion.2.With the surgical treatment of abdominal transhiatal approach, Open andlaparoscopic-assisted therapy can achieve the same curative effect.3.R1resection AEG effects the survival time of patients Significantly,thefactors effect survival time of R0resection including tumor Siewert types,TNM stage, tumor histological grade and vascular invasion,and there is nosignificant correlation with sex and surgical approach.