| [Objective] Vaccinate infants withoutvaccination before using lyophilized measles vaccine withdifferent titer potency, which can provide evidences to controland eliminate measles.[Method] Vaccinate infants without vaccination before andinfants without getting measles, after that, observe theirclinical reaction carefully. At the same time, test their serumantibody level before immunity and immunity。[Result] In aclinial trail of vaccinated infants,their clinical reactionswere slight, fever happened5.7%of cases, papulo-vesiculareruptions appeared4.3%;local reaction happened2.8%.Thetesters tested serum antibody IgG using ELISA, they found theseroconversion of serum antibody appeared95.23%,thesuccessful result of immunity is86%,the GMT got to1364.22inA team. The seroconversion of serum antibody appeared97.11%,the successful result of immunity is86.13%the GMT got to1275.74in B team. There is no statistical significance betweenA team and B team on seroconversion of serum antibody, thesuccessful result of immunity and GMT.[Conclusion] The infantswill get good respond effect after vaccinating measles vaccinewhen the titer potency qualifies Pharmacopoeia of The People’sRepublic of China. |