The TCM Syndrome Of Acute Cerebral Infarction And Serum Levels Of ET-1, VWF, H-FABP, PAO Correlation Research

Objective:Through the study of acute cerebral infarction patients with different TCM syndrome types of acute stage blood ET-1, v WF, H-FABP, PAO content changes, to explore the TCM syndro me of acute cerebral infarction and related biological indexof the re lationship, from the Angle of microcosmic syndrome differentiation,c larify acute cerebral infarction in acute stage of TCM syndrome an d the related factors of serum.Method:ELISA method is used to test90cases of acute cerebral infarction patients with the acute phase (wind syndrome group15c ases, heat syndrome group15cases,15cases of phlegm syndrome group, group of15cases of blood stasis syndrome, qi deficiency sy ndrome group15cases, Yin hand card group15cases) and15cas es of normal healthy subjects, vWF, serum levels of ET-1H-F ABP and PAO content changes. Through each card type group and normal control group the ratio of each index, after transformation, the research and the acute cerebral infarction, the correlation of eac h syndrome type of traditional Chinese medicine.Results:(1) the case group serum levels of ET-1value compare d with normal control group, except the qi deficiency, Yin deficien cy hand two group were higher (P＜0.05); The highest heat syndr ome group, the wind syndrome, blood stasis syndrome, qi deficienc y syndrome, Yin deficiency hand between groups, P＜0.05; Phleg m syndrome, blood stasis, wind three high in the qi deficiency, Yin deficiency hand two group, P＜0.05;(2) heat syndrome, phlegm, blood stasis syndrome of three groups of serum vWF content value s are higher than normal control group (P＜0.05); Highest heat sy ndrome group; Phlegm syndrome group take second place; Third of blood stasis syndrome;(3) heat syndrome, phlegm syndrome, the wind of three groups of serum H-FABP content value is higher t han normal control group (P＜0.05), the highest heat syndrome gr oup, phlegm syndrome, wind group take second place;(4) the conte nts of serum PAO card type value compared with normal control g roup, in addition to the Yin deficiency hand group were higher (P＜0.05); The highest heat syndrome group (P＜0.05); Phlegm synd rome group take second place; The wind syndrome, blood stasis gr oup again. Conclusion:The TCM syndrome of acute cerebral infarction with s erum levels of ET-1, vWF, H-FABP and PAO is closely relate d to the content, Serum levels of ET-1, vWF, H-FABP and P AO content on acute cerebral infarction, cerebral ischemia and the evaluation of brain injury has important clinical practical value. Can be used as acute cerebral infarction, the doctor of traditional Chin ese medicine syndrome differentiation and classification of the objec tive indicators, also can be used as biological indicators in early di agnosis of acute cerebral infarction.