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The Study Of The Harmful Elements Of The Gypsum Mineral Medicine

Posted on:2014-01-04Degree:MasterType:Thesis
Country:ChinaCandidate:J H WangFull Text:PDF
GTID:2244330395491512Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
Gypsum is beginning in the book of Sugababes which Classified in goods in the article. The main components in aqueous include calcium sulphate, zinc, copper, iron, manganese and also rich in trace elements. Gypsum mainly produced in Hubei, Anhui, Henan, Shandong, Sichuan, Gansu, but Hubei yingcheng and Anhui Fengyang are the most famous place of production. TCM clinical all use cruded and Calcined Gypsum, which have different efficacies. Raw Gypsum has the effect of clearing heat and excepting bother. It can cure high heat polydipsia, asthmatic cough, toothache, headache. Calcined gypsum has effect of hygroscopic, bomning muscle, Severing boils convergence and hemostasis.It used for ulcer which is not gathered, itching, distortion and burns. Modern pharmacological studies have shown that Gypsum have the effect of antipyretic,sedative, and anti-inflammatory. Gypsum contains lead, mercury, arsenic, cadmium and other harmful elements,which derived from natural ore, may do harm to human health. Gypsum is applicated commonly as a Chinese medicine.In order to guarantee the safety of the drug, it is necessary to study the content of harmful elements in Gypsum.In this study, a systematic study of the harmful elements in the Gypsum have been studied and researched its drug safety.The research mainly includes the following aspects:Using atomic absorption spectrophotometry (AAS) and diethyldithiocarbamate carbamate silver (Ag-DDC)determined harmful elements of lead, arsenic, cadmium, mercury and copper in samples of12commercially available Gypsum. The results showed that the harmful elements are detected and some of which are in excess of standard concentration.Investigated the Technology of Gypsum. Select the temperature, time, particle size, as three factors and the dissolubility of harmful element as an index, then conduct Orthogonal analysis.Determine the best processing technology:of Gypsum as heat650℃, calcined0.5h forged size into small pieces.The dissolubility of five harmful elements lead, cadmium, arsenic, mercury and copper were tested in water solution and gastric intestinal juice. Results showed that the content of harmful elements were below the regulation limits. Gypsum is safe in clinical.
Keywords/Search Tags:Gypsum, harmful elements, Processing technology, Dissolution quantity
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