Study On Absorption Of Carbon Dioxide Using Organic Amine And Its Perfbrmance

In order to find some lead compounds with activities of anti-cancer, a series of novel N-(substituted benzyl)-3,5-bis(benzylidene)-4-piperidones (Ia-Ij) were synthesized with substituted benzylamines as raw materials via a series of Michael addition, Dieckmann condensation, hydrolysis decarboxylation and Aldol condensation. The structural formulas of compounds (Ⅰ) are as follows:All these target compounds are new compounds and their structures wereconfirmed by IR,1H NMR, MS, and elementary analysis. Their physic-chemical properties, spectrum properties, reaction conditions and synthetic methods were discussed as well.The preliminary biological activities tests of target compounds (Ⅰ) were finished in the Zooblast-molecular biology laboratory of Shanghai Normal University. The preliminary biologic activity tests indicate that some of the target compounds have good antiproliferative activities against K562, MDR-MB-231and HO8910PM cells, have potential antitumors bioactivity.