Recognition Performance Of Novel Au Functional Nanomaterials As Probe

Gold nanoparticles have been widely used in the field of analytical chemistry because of its specialoptical and electrical properties. Recently, functionalized gold nanoparticles as probes are widely used indrug, food safety, environmental and biological analysis, biological labeling and imaging fields. Goldnanoparticles （13nm） shows wine red, the maximum absorption wavelength at520nm, the design andsynthesis of gold nanoparticles with special functions and have special interaction to targeting molecules,induction of aggregation, by wine red to purple or blue, which is attributed to the plasma coupling betweenthe nanoparticles, this phenomenon can be used to a new method for the molecular detection. At the sametime, the method has the advantages of short time, high selectivity, and does not require expensive andcomplex instruments and so on. It has broad application prospects. This paper mainly focuses on thesynthesis, modification and properties of gold nanoparticles in the metal ions and small organic moleculedetection.1. Design and synthesis of4-amino-3-hydrazino-5-mercapto-1,2,4-triazol modified gold nanoparticleprobes, studied the recognition performance of the probe, through the complexation high sensitive detectionof Cd²⁺and high selectivity, high sensitivity detection of dopamine by hydrogen bonds. The method isbased on Cd²⁺and dopamine can induce the aggregation of gold nanoparticles resulting in the opticalproperties of gold nanoparticles changed, the color of the solution red turns to blue. The experimentalphenomena based on the new method for the determination of Cd²⁺and dopamine is established. Thismethod is simple and convenient, and does not need expensive equipment.2. Design and synthesis of thiotrzinone modified gold nanoparticles, studied the recognitionperformance of the probe, through the complexation of high sensitive detection of Cr³⁺, and high selection,high sensitive detection of dopamine and melamine by hydrogen bonding. The method is based on Cr³⁺,dopamine and melamine can induce the aggregation of gold nanoparticles resulting in the optical propertiesof gold nanoparticles changed, the color of the solution with red turns to blue. A new method for thedetermination of Cr³⁺, dopamine and melamine was established by those experimental phenomena. Thismethod is simple and convenient; the whole process can be observed with naked eyes and does not needexpensive equipment, in the actual samples also exhibited excellent performance. 3. Design and synthesis of2-Amino-6-hydroxy-8-mercaptopurine modified gold nanoparticles, studiedthe recognition performance of the probe, through the complexation of high sensitive detection of Cr³⁺, andhigh selection, high sensitive detection of dopamine and melamine by hydrogen bonding. The method isbased on Cr³⁺, dopamine and melamine can induce the aggregation of gold nanoparticles resulting in theoptical properties of gold nanoparticles changed, the color of the solution with red turns to blue. A newmethod for the determination of Cr³⁺, dopamine and melamine was established by those experimentalphenomena. This method is simple and convenient; the whole process can be observed with naked eyes anddoes not need expensive equipment, in the actual samples also exhibited excellent performance.4. Design and synthesis of2-thiobarbituric acid modified gold nanoparticles, studied the recognitionperformance of the probe, through the complexation of high sensitive detection of Cr³⁺, and high selection,high sensitive detection of dopamine and melamine by hydrogen bonding. The method is based on Cr³⁺,and dopamine can induce the aggregation of gold nanoparticles resulting in the optical properties of goldnanoparticles changed, the color of the solution with red turns to blue. A new method for the determinationof Cr³⁺and dopamine was established by those experimental phenomena. This method is simple andconvenient; the whole process can be observed with naked eyes and does not need expensive equipment, inthe actual samples also exhibited excellent performance.