Radical Cation Induced Cycloaddition Reaction To Build Quinoline Skeleton

This thesis is mainly composed of three parts. In the first part, the synthesis oftetrahydroquinolines, and quinolines was reviewed. Then a radical cation saltcatalyzed Povarov reaction was investigated and a series of quinolines weresynthesized in high yield. Finally, a domino cyclization induced by the radical cationswas studied.The main contents are as follows:1、Recently, we found an efficient and simple method to synthesize the quinolines.via the reaction of ethyl glyoxylate imine and N-vinylamide. The method reduces thecosts, shorten the reaction time, and simplify the reaction steps.2、In this section，a radical cation catalyzed reaction of glycines was explored. Wefound that the reaction of glycines with N-vinylamides can occur smoothly underradical cation induced conditions and a series of tetrahydroquinolines were obtainedin high yields.