Design, Synthesis And Activity Analysis Of High-yield Agent For Cotton Crops

Cotton fiber is the most important natural fiber, occuping an important position inthe sustainable development of the textile industry. However, the supply and demand ofcotton is out of balance. How to increase the output of cotton becomes one of thehotspots. Using nitrogen fertilizer efficiently is a major factor in increasing the output ofcotton. Slowing the decomposition of urea is an important way to improve nitrogen useefficiency. Basing on its diversiform structure and unique performance, Schiff base metalcomplex has a wide range of research prospects in scientific fields of chemistry, biology,medicine, materials and so on. Some Schiff base complexes have the significantbiological activity in antibacterium and inhibiting urease. Therefore, taking urease as atarget and selecting Schiff base complexes as lead compounds become one of theimportant methods to increasing the output of natural fiber crops.In this paper, the author has carried on the condensation reaction using5-bromosalicylaldehyde and2-hydroxy-1-naphthaldehyde respectively with2-hydroxybenzoylhydrazine,4-hydroxybenzoylhydrazine,2-chlorobenzohydrazide, and gotsome Schiff base intermediates. Besides adding diethylamine, triethylamine, KSCN,N,N-dimethylformamide and other small molecule ligands, Cu (II) is coordinated tocultivate a series of Cu (II) complexes.11kinds of new Schiff base metal complexes,acyl hydrazones as tridentate O,N,O–donor chelating ligands, have been synthesized. Thestructures of these new Schiff base metal complexes have been characterized byelemental analysis, infrared absorption, ultraviolet absorption test methods, and theircrystal structures have been analyzed using X-ray diffraction.In addition, the Schiff base complexes, which have been synthesized in this paper,have been studied on inhibiting urease biological activity. The results show that eightkinds of complexes have a certain effect to inhibit urease activity (The order of thecapability inhibiting urease activity:8>7>10>11>2>1>9>4). Besides, the relationship between the capability of inhibiting urease activity and its structures has beendiscussed and analyzed. The results show that the kind of anionic ligands, the sites ofsubstituent groups and their space structures have all some impact on the ability toinhibiting urease activity. Analyzing the relationship between the capability to inhibiteurease activity and structures of metal complexes helps us to design and synthesize moreideal urease inhibitors.