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Synthesis And Properties Of New Novel Rhodamine Fluorescent Compounds

Posted on:2014-02-08Degree:MasterType:Thesis
Country:ChinaCandidate:M LiFull Text:PDF
GTID:2251330425490565Subject:Inorganic Chemistry
Abstract/Summary:PDF Full Text Request
With the developing of society and the improving of living standards, how to maintain the balance of biological and environment become the focus of attention. Then, how to detection the components of surroundings has become one of important topic in the field. Especially with the development of medical science, biological science, environmental science and other aspects, it is a good research platform for the detection of the material.In many of the detection technology, fluorescent molecular probes technology because of its high sensitivity, visibility, quick and easy; also there is no damage and interference for the study of biological macromolecules or target cells. It has been got a wide range of applications. Now, fluorescent probes have played an important role in the detection of heavy metals, oxygen-containing acids, amino acids, acid-base nature and so on, especially, rhodamine derivatives. The rhodamine framework is an ideal model to construct fluorescent chemosensors due to its high sensitivity, high selectivity, the stability of optical properties, high fluorescence quantum yield and "on-off".In this thesis, we summarized the research progress of rhodamine fluorescence chemical sensor, as well as the abilities to selectively bind and sense. On this basis, a series of rhodamine derivatives as reporting group were synthesized and identified by1H NMR,13C NMR, and elemental analysis. The properties of probes were analyzed by fluorescence spectroscopy and UV-vis.Finally, we synthesized the compound2-3that can be detected Hg2+and HOCl separately in different systems, the compound2-5that can be detected H+under certain conditions, as well as the compound2-7that can be selective detected heavy metals Fe3+.They can be successfully applied for bioimaging detection in living cells.
Keywords/Search Tags:rhodamine fluorescence sensor, Hg2+, Fe3+, HOCl, H~+
PDF Full Text Request
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