| In recent years, core-shell structure composite nanoparticles combined of noble metal nanoparticles and fluorophore have unique physical and chemical properties, therefore, they have a broad prospect of application in biomedical field, such as drug transmission, DNA sequence detection, disease diagnosis and treatment, fluorescence probe and biological imaging, etc. And they have been attracted great interest of the researchers. The research of interaction of luminescence properties between noble metal nanoparticles and fluorophore will have important reference value for synthetic high-efficiency luminescent materials. In this thesis, Ag nanoparticles were prepared by liquid phase and hydrothermal method, and then the core-shell structure Ag@GdF3:Er3+,Yb3+, Ag@GdF3:Er3+,Yb3+@SiO2, Ag@SiO2@GdF3:Er3+,Yb3+and Ag@SiO2@GdF3:Er3+,Yb3+@SiO2up-conversion luminescence nano-particles were successfully synthesized by direct precipitation method. The structure and luminescence properties of the samples were characterized by XRD, TEM, FTIR, UV-Vis, and fluorescence spectra. Changing the amount of TEOS and the amount of rare earth nitrate can effectively control SiO2layer thickness and the thickness of rare earth shell, and then tune the luminous performance. The outer SiO2layer can improve the stability, water soluble and biological compatibility of core-shell structure nanoparticles, which would be widely used in biomedical and related fields. |
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