Synthesis Of Chiral Supramolecular Nanomaterials And Chiral Thiourea-based Chemodosimeter For Mercury Ion

With the rapid development of supramolecular chemistry, supramolecular research has focused on the building of chiral supramolecule, which has widely used in molecular recognition and nanomaterials. Molecular recognition includes neutral molecules, cation and anion recognition, and chiral nanomaterials comprise quantum dots, metal nanoparticles and inorganic nanocrystals.This thesis is mainly about chiral nanoparticles and cation recognition. It includes three chapters:In chapter1, the forces and assembly ways of chiral supramolecule have been introduced. With the progress of chiral nanomaterials, Hg2+sensing based on fluorescence and circular dichroism (CD) methods, the content, purpose and significance of this study are presented.In chapter2, we synthesized chiral cysteine stabilized HgS NCs according to the interaction of intrinsically chiral materials a-HgS and chiral amino acid, which was easily prepared in aqueous solution at room temperature. As we expected, the majority rules effect was operative in this system, which was indicative of chiral amplification. It is expected that our research would contribute to the development of chiral biosensing and facilitate further advance in chiral nanomaterial research and catalysis. Chiral communication will provide new ideas to generate new nanomaterials.In chapter3, we employed L-/D-DPPCA as novel CD-based chemodosimeters to detect Hg2+selectively, which underwent desulfurization reaction in pure water, so that the CD spectral changed dramatically. Chiral communication can transfer from amino group to the thiourea moiety due to the Hg2+-promote reaction. Hg2+receptor molecules were with a high selective and anti-jamming capability, Moreover, mercury-promote cyclization converts mercury ion into HgS which was easy to remove, which allowed for simultaneous sensing. Thiosemicarbazide group can serve as linking arm for designing new fluorescent and colorimetric or electronic sensors of Hg2+. We expect it will provide new ideas for the development of testing toxic ion in the water environment.