A Goggle Navigation System For Cancer Resection Surgery

Over the last few years, near-infrared (NIR) fluorescence imaging has witnessed rapid growth and is already used in clinical trials for various procedures. However, most of the navigation imaging devices(such as MRI, CT and PET) are bulky and can not be used to achieve the fully dynamic navigation in the operation room. Some of the devices will also cause damage not only to the surgeons but also to the patients. In recent years, The development of the molecular imaging technology creates a good condition for the emergence of the navigation imaging system. But the now exist navigation devices are not only expensive but also unsuitable to the real time operation for the surgeons.To overcome the limitation of now exist imaging system, We describe a portable fluorescence goggle navigation system for tumor margin assessment during oncologic surgeries. The system consists of a computer, a head mount display (HMD) device, a near infrared (NIR) CCD camera, a miniature CMOS camera, and a780nm laser diode excitation light source. The fluorescence and the background images of the surgical scene are acquired by the CCD camera and the CMOS camera respectively, co-registered, and displayed on the HMD device in real-time.The technical feasibility of the proposed goggle system is tested in an ex vivo tumor model. Our experiments demonstrate the feasibility of using a goggle navigation system for intraoperative margin detection and surgical guidance.