The Finite Element Analysis Of Deep Brain Stimulation

Deep brain stimulation has became the effective method for the treatment ofmovement disorders in the past twenty years. so far, DBS has entered into the treatment ofgilles DE la tourette syndrome, obsessive-compulsive disorder, depression, epilepsy,cluster headaches in the experimental stage. and the corresponding method is alsogradually be applied to the clinical, electrophysiological experiment, biochemical analysis,computer simulation of imaging studies.The purpose of this study is to explore electric field produced by implantedelectrodes in the brain and nerve tissue response to plus stimulation mechanism, thusprovide certain theoretical guidance for clinical stimulus options. Digital simulationresults show that:(1) applying electrical stimulation, in acute stage, GPi gray ballsaccounts for88.23%of the total current and the rest into white matter; in Chronic phase,the GPi gray balls accounts for94.04%of the total current;(2) if the threshold valuebetween electrode electrode is greater than0.18V, the adjacent electrodes area willoverlap,(3) under the same external stimulus, the greater the diameter of the neurons, themore prone to action potential conducts, and the action potential conduction velocity isfaster; and the smaller of node space, the easier of action potential conducts, but altoughthe distance is large enough, the increase of conduction rate is not obvious;(4) doubleelectrode and four electrodes stimulation mode are enhanced the VTA, but in close doubleelectrode and distanced double electrode stimulation mode, the activated area decreasesand there was a "dead zone" between the two electrodes, the farther of the electrodedistance, the less of corresponding activation area(5) the distribution of temperature fielddepends on the applied stimulus parameter and physical parameter of tissue inside, thisarticle studies the temperature change rate is less than0.2℃.