| Rheumatoid arthritis (RA) is an autoimmune disease, Symmetric poly-arthritis is the main clinical symptoms. Chinese Traditional Medicine(TCM) believes that RA belongs to the areas of a TCM disease called "Bibing", also known as "Bizheng","Lijiefeng","Hexifeng", Professor Shude Jiao first proposed the name of "Wangbi". Patients who suffer from long-term disease-ridden, show anxiety, depression and other psychological state. These psychological states, in turn, affect the clinical treatment, thus forming a vicious cycle. Currently, medicine treatment can improve the patient’s condition to a certain extent, but can not effectively improve joint function and patients’ mental health. TCM shows a unique advantage in the treatment of RA clinical applications, The integrated use of TIP and tai chi, called TIP integrated intervention, can give better play to the characteristics of Chinese medicine treatment, play a role in physical and mental adjustment, achieve physical and mental adjustment.Purpose:The subject preliminary study on the role of TIP integrated intervention in RA clinical treatment, observed TIP integrated intervention’s effects on physiological function, psychological state and quality of life of the patients.Method:In this study we chose Rheumatology3-month clinical follow-up clinical data as the research object, pain VAS score, DAS28score, Joint function classification, HAQ score, SAS score, SDS score, SCL-90scale as the main evaluation.60patients who met the inclusion criteria, were randomly divided into control group and intervention group,30cases in each. Control group used conventional drug therapy (TCM Syndrome differentiation and treatment with DMARDs) in the outpatient for3months, and the intervention group was treated with conventional drug therapy(TCM Syndrome differentiation and treatment with DMARDs) in outpatient and TIP integrated intervention(TIP and tai chi first to tenth actions), twice a week,60min each time, for three-month treatment period.The subject observed two groups of patients with RA pain VAS score, DAS28score, the joint functional class, HAQ score and SAS score, SDS score, SCL-90scale score changes. Result:1.Group comparisons:Control group in pain VAS score, DAS28score, SAS score, SDS score, SCL-90factor scores (somatization, depression, anxiety and positive symptoms), HAQ score before and after treatment has significantly different (p<0.05). The joint function classification, SCL-90score (obsessive-compulsive, interpersonal relationships, hostility, terror, paranoia, psychosis, Total and sharing score), had no significant difference (p>0.05); Intervention group in VAS pain score, DAS28score, joint function classification, SAS score, SDS score, SCL-90factor scores (somatization, interpersonal sensitivity, depression, anxiety, Total, total score and positive symptoms sharing), HAQ score before and after treatment has statistically significant differences (p<0.05)。2.Comparison among groups:Two groups in pain VAS score, DAS28score, joint function classification, SAS score, SDS score and HAQ score, have significant difference, and the intervention group improves significantly better than the control group (p<0.05); In SCL-90scores, somatization, obsessive-compulsive, interpersonal relationships, depression, anxiety, Total score, sharing score and positive symptoms sharing score have a significant difference (p<0.05), and the intervention group was better than the control group; while, differences of the two groups in hostile, terror, paranoia, psychotic, are not statistically significant (p>0.05).3.Comparison of efficacy:Efficacy of DAS28score, SAS score, SDS score and the overall improvement rate of the disease (ACR20) in intervention group is significantly better than the control group (p<0.05); The efficacy of pain VAS score and HAQ score in two groups are no significant difference (p>0.05).Conclusion:1.The mental health level of RA patients is lower than the normal population, Anxiety and depression state was more obvious, and SCL-90factor scores mainly reflected in the following aspects:somatization, depression, anxiety, hostility, terror, paranoid and psychotic. In the treatment, we should actively implement the psychological intervention to improve the mental health of patients.2.TIP integrated intervention is better to improve the patients’ physiological function, reduce RA disease activity, and improve joint dysfunction.Tai chi can be used as one of the joint functional exercises. 3.TIP integrated intervention can effectively alleviate the patient’s anxiety and depression, improve the patient’s symptoms of somatization, obsessive-compulsive symptoms, interpersonal relationships, depression and anxiety performance, thus significantly improve the patient’s level of mental health.4.TIP integrated intervention can effectively improve the quality of life of patients by improving the patient’s physical symptoms and mental health.5.TIP integrated intervention with high safety of clinical application, has the dual role of physical and mental conditioning, it not only has the application value in the treatment of RA, but should be also promoted and applied to the treatment of other physical and mental diseases.6.TIP integrated intervention is the integrated use of TCM psychology and TCM Qigong Science (TCM rehabilitation science).It has strong characteristics of TCM, and reflects the advantages of Chinese non-medicinal method with the value and prospects of further study. |