| ObjectiveTo compare uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), spherical aberration, contrast sensitivity and visual function after implanting Humanoptics MCX11ASP aspherical intraocular lens and AS spherical intraocular lens.Methods1. The prospective clinical control study. Age-related cataract patients presented in our hospital from June-December of2011were selected and received preoperative examination (such as slit lamp examination, fundus examination,(A, B) scan were taken and corneal curvature, intraocular pressure, ERG and VEP were examined). Corneal diseases, glaucoma, uveitis, lens subluxation, retinal diseases, high myopia were excluded. All patients were divided into two groups according to their wills. Humanoptics MCX11ASP aspherical intraocular lens was implanted for group A; AS spherical intraocular lens for group B.2. Postoperative screening criteria:Routine ophthalmologic examinations were taken for all postoperative follow-up patients. Cornea pathological change, iris atrophy and depigmentation, abnormal pupil direct and consensual light reflex, pathological changes of retina and vitreous, postcapsular opacification were excluded. There were not decentrations, tilt, damagements in intraocular lens.3. Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), contrast sensitivity, wavefront aberration, refractive errors were assessed in these cases.4. These indexes were analyzed by SPSS13.0statistical software.Results1. Routine ophthalmologic examinations were taken for all patients1week post-operation. In the follow-up of1month post-operation,3patients (4eyes) were lost. In the follow-up of3months post-operation,5patients (7eyes) were lost.78patients (96eyes) were selected,30patients (36eyes) in group A and48patients (60eyes) in group B.2. The dipoters of intraocular lens of group A were21.23±2.16(D),21.97±2.24(D) for group B. No statistical difference was found between these two groups (P=0.0936). Decentrations of intraocular lens (≤0.25mm) were found in6patients (6eyes),2patients (2eyes) in group A and4patients (4eyes) in group B. Refractive errors were examined3months post-operation. Defocus of group A was-0.1875±0.5806D,-0.1258±0.6159D for group B. No statistical difference was found between these two groups (P=1.000). Astigmatism of group A was0.5486±0.3526D while0.5333±0.3459D for group B. No statistical difference was found in these two groups (P=0.8354).3. Mean uncorrected visual acuity of group A1W,1M,3M post-operation was0.35±0.16,0.43±0.20,0.58±0.18, which of group B was0.31±0.18,0.38±0.25,0.54±0.17. There were no significant differences between A and B groups (P>0.05). Mean best-corrected visual acuity of0.91±0.12of group A was not significantly different from0.88±0.11of group B (P=0.2143). The pupil diameters of the two groups were3.49±0.53(mm) and3.48±0.53(mm), no significant difference (P=0.9289).4. Group A had higher contrast sensitivity than group B in6.3°visual angle with or without glare while similar in4.0°,2.5°,1.6°,1.0°,0.7°visual angle3months post-operation (P<0.01).5. Mean spherical aberration and coma of group A were not significantly different from group B when pupil diameters were3～4mm (P>0.05). When pupil diameters were5.0mm, mean spherical aberrations of two groups were0.050±0.046μm,0.120±0.095μm respectively. Mean coma of group A was0.150±0.095μm, group B0.202±0.129μm. There were significant differences between these two groups (P1=0.001, P2=0.0385).Conclusion1. Mean uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA) of MCX11ASP group are not significantly different from AS group3months post-operation.2. In6.3°visual angle (low spatial frequency), the contrast sensitivity of MCX11ASP group is better than that of AS group.3. MCX11ASP aspherical intraocular lens can reduce the positive spherical aberration of eyes compared to AS spherical intraocular lens when PD is5.0mm, thus improve visual performance. |
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