Correlation Between Blood Pressure Variability And Mean Platelet Volume In Hypertension Patients With Carotid Atherosclerosis

Objective: To observe the changes of blood pressure variability (Blood pressurevariability BPV) and mean platelet volume in hypertension patients with carotidatherosclerosis, to explore the correlation between BPV and MPV.Methods:110caseshospitalized from September2010to June2012at the Fifth Affiliated Hospital of XinjiangMedical University, and all the people60-75years of age meet the inclusion criteria ofpatients with essential hypertension. All patients were performed color doppler ultrasound,according to the carotid artery intima-media thickness(IMT) were divided into twogroups：Group A is one of essential hypertenaion with normal IMT of54persons, Group Bis one of hypertension with IMT thickening of56persons. For selected patients24h-hourambulatory blood pressure monitoring, calculating each patient BPV related index. Testthe level of MPV, three groups of test results were compared and analyzed thecharacteristics of each BPV、MPV value, analysis the relationship between BPV and MPV.Result: Hypertension with IMT thickening group of24hSBPSD,24hSBPCV, dSBPSD,dSBPCV, nSBPSD, nSBPCV, and MPV level are higher than the pure hypertension group.Hypertension with IMT thickening group of MPV value and24hSBPSD、24hSBPCV、dSBPSD、d SBPCV、n SBPSD、nSBPCV into positive correlation (p <0.05).Conclusion:Hypertension with carotid atherosclerotic patients BPV increases, the higher level of MPV.Patients with high blood pressure can promote platelet activation reaction, promote thehypertension patients carotid atherosclerosis occurrence and development...