The Case-control Study Between Thyroid Carcinoma And Urine Iodine In Urmuqi

Objective:To Investigate the relationship between thyroid carcinoma and urineiodine in Urumqi,and to provide the evidence of individual iodine supplement of thisregion.Methods: A case-control study,100cases with thyroid carcinoma treated inXinjiang Tumor Hospital between February2012and December2012as the casegroup,all the patients were cured by the surgery of thyroid cancer/neck combined radicalsurgery,pathologically confirmed thyroid cancer,meanwhile300cases with normal thyroidfunction came from the examination Center of the same hospital as the control group.Allthe cases were detected for urine iodine concentration by arsenic-cerium catalyticspectrophotometry.Result:(1)The mean urinary iodine in the case group (272.69μg/L)washigher than the control group (161.40μg/L),there was statistically significant difference（P>0.05）;The mean urinary iodine in the case group was higher than the control group indiffrient sex(male,female)、age（≤45,＞45）（P＜0.05）;There were34cases accountedfor34%(34/100) of excessive iodine intake (urinary iodine>300μg/L) in the casegroup,in control group there were30cases accounting for10%(30/300)，there wasstatistically significant difference(P<0.05).（2）The majority of the control group and thecases group are in state of iodine amount，at the same time there still have a certainpercentage of the iodine intake of excessive iodine intake.Conclusion: This study showedthat the average urinary iodine content of the thyroid carcinoma in this region weregenerally higher than the healthy control group, indicating that the iodine nutritionalstatus of patients with thyroid carcinoma better than the general population,there have acertain relationship between the disease and excessive iodine intake.