Clinical Significance Of Time-signal Intensity Curve Type Ⅱ On Dynamic Contrast-enhanced MRI Of The Breasts

Objective:To explore the value of time-signal intensity curve(TIC)type Ⅱ inidentifying enhanced lesions of the breasts on dynamic contrast-enhancedMRI(DCE-MRI),to provide a more reliable evidence for clinical work. Materials andmethods:39patients with breast lesions performed MRI examinations at1.5T scanner.Numbers and features of the lesions were analyzed on axial FSE T1WI, axial STIRT2WI, and3-dimentional DCE-MRI after intravenous gadolinium administration. TICtypes of the enhanced lesions were classified according to their shapes. Pick out type Ⅱto analysis. Results: Among39female patients, the left breasts21，the right breasts18,abnormally enhanced lesions with TIC type Ⅱ on DCE-MRI included Benign lesions in21（54%），(Breast adenosis3, Breast fibroadenoma18), Malignant lesions in18(Ductalcarcinoma in situ1, Medullary carcinoma4,Invasive ductal carcinoma13). TIC type Ⅱ tojudge the malignant and benign breast disease, sensitivity was88.33%, specificity42.86%,positive predictive value55.56%,negative predictive value75.00%.Conclusion:TIC type I may be found in both benign and malignant lesions of the breasts, it isnecessary to combine with clinical history and MRI morphological characteristics,BI-RADS-MRI degree, after the enhanced scan data for a correct judgment to breastdisease.