Single Cardiac Cycle Three-dimensional Echocardiography In The Study Of Left Ventricular Function And Synchronicity On Coronary Heart Disease Before And After Percutaneous Coronary Intervention

Objective: single cardiac cycle real-time three-dimensional echocardiography (sRT-3DE)evaluates left ventricular function and synchronicity the early changes of left anteriordescending coronary artery (LAD) of acute myocardial infarction (AMI) and chronic stablecoronary artery disease after percutaneous coronary intervention (PCI) operation, andcorrelation of left ventricular function, synchronicity and degree of coronary artery stenosis,provides preoperative assessment and PCI postoperative short-term curative effectevaluation.Methods: choose LAD PCI patients with AMI (39cases) and chronic stable coronaryartery disease (48cases), sRT-3DE examination for preoperative and postoperative1week,get left ventricular function and synchronicity parameters. left ventricular functionparameters: ejection fraction(EF), stroke volume(SV), end-systolic volume(ESV),end-diastolic volume(EDV), end-systolic sphericity index(ESSI), end-diastolic sphericityindex(EDSI); left ventricular systolic synchronicity parameters: systolic dyssynchronyindex16-segment model(SDI16), dispersion in end systole16-segment model(DISPES16), mean end-systolic time16-segment model(MES16), pre-contraction time volume16-segment model(Pre Contr16), post-contraction time volume16-segment model(PostContr16), left ventricular diastolic synchronicity parameters: diastolic dyssynchrony index16-segment model(DDI16), dispersion in end diastole16-segment model(DISPED16),mean end-diastolic time16-segment model(MED16), pre-relaxation time volume16-segment model(Pre Relax16), post-relaxation time volume16-segment model(PostRelax16). For above parameters, divide AMI and chronic stable coronary artery diseaseinto mild, moderate and severe three groups according to revised Gensini score, groupstudy compares parameters variation between preoperative and postoperative, analysis ofthe correlation between all patients16preoperative parameters and degree of coronaryartery stenosis. Statistical software analysis was carried out by SPSS17.0, preoperativeand postoperative parameters before and after PCI operation were compared with Paired t test, Correlation analysis with Spearman correlation analysis; Significant levels are all forα=0.05,P <0.05was considered to be statistical difference.Results: after PCI operation1week, mild, moderate and severe AMI group EF and SVare upper than preoperative(P＜0.05), ESV, EDV, ESSI, EDSI, SDI, DISPES, MES, PreContr, Post Contr, DDI, DISPED, MED, Pre Relax and Post Relax are lower thanpreoperative(P＜0.05); after PCI operation1week, mild and moderate chronic stablecoronary artery disease group EF, SV, ESV, EDV, ESSI, EDSI, SDI, DISPES, MES, PreContr, Post Contr, DDI, DISPED, MED, Pre Relax and Post Relax had no statisticalsignificance compared with preoperative(P＞0.05), severe chronic stable coronary arterydisease group EF and SV are upper than preoperative(P＜0.05), ESV, EDV, ESSI, EDSI,SDI, DISPES, MES, Pre Contr, Post Contr, DDI, DISPED, MED, Pre Relax and PostRelax are lower than preoperative(P＜0.05), There is no correlation between leftventricular function, synchronicity and degree of coronary artery stenosis.Conclusion: AMI patients left ventricular function and synchronicity improved after PCIoperation1week, mild and moderate chronic stable coronary artery disease patients withlow revised Gensini score left ventricular function and synchronicity had no obviousimprovement after PCI operation1week, severe chronic stable coronary artery diseasepatients with revised Gensini score higher left ventricular function and synchronicityimproved after PCI operation1week.