The Relativity Analysis Of Sputum Bacterial Cultures Positive Rate And The Influence On Severity Of Children Suffered From Respiratory Tract Infection

Objective:Respiratory tract infection is a common and frequently-occurring disease for children, the existing researches have showed clear evidence that viruses and bacteria are the main pathogens of respiratory tract infection. In this study, the clinical features of children encountered respiratory tract infection caused by bacteria and/or viruses in Chongqing will be analyzed, to make it clear that viruses coinfected bacteria have an affect on disease severity and duration of hospitalization or not, so as to provide some guidance for clinical prevention and control.Methods:Clinical information of1745cases was collected from June2009to June2011in respiratory ward of our hospital, and1157cases who had been accepted sputum bacterial cultures were chose. Bacteria culture results and respiratory common viruses detection results were retrospectively analyzed, to analyze the pathogens and clinical manifestations.Results:677strains of bacteria were separating out from1157cases, the average positive rate was58.5%. Among them G-bacteria accounted for above45.3%, and streptococcus pneumoniae was at the first place, Haemophilus parainfluenzae was the second. In addition to escherichia coli, positive rates of other5bacteria were higher in winter and spring. Children whose sputum cultures were positive focused on younger children, especially within3years old, different bacteria in different ages distribution were not statistically significant. Sputum culture results had no affect on cough, fever, dyspnea, wheezing, WBC and Neutrophilic granulocyte ratio, however, they had an affect on duration of hospitalization. Klebsiella pneumoniae tended to cause severe pneumonia,and OR=2.933. RSV, ADV coinfected with bacteria in causing severe pneumonia or not were not statistically significant.,but RSV infection with positive streptococcus pneumoniae in sputum culture tended to cause wheezingConclusions:This study further demonstrated that G-bacteria were the majority in all sputum bacterial cultures. The duration of hospitalization of children whose sputum bacteria cullture was positive was longer. Positive Klebsiella pneumoniae in sputum bacterial cultures tended to cause severe pneumonia. Positive sputum bacterial cultures had no significant influence on the pneumonia severity caused by RSV or ADV infection.