The Morphological Changes Of The Microvascular And Surrounding Tissue Of The Steal Blood Area Around The Intracranial Arteriovenous Malformations

The purpose is to explore the morphological structure changes of capillaries in steal blood area and the surrounding tissue surrounding AVM, giving researches of the reasons and mechanism and causes of the clinical symptoms of the steal blood area capillaries, in order to support the morphological structure changes of capillaries in steal blood area, Speculating the causes of recrudescence of AVM prognosis and complications.Methods:Select20patients with AVM who choose surgical treatment in Xiangya hospital of Central South University from April-August of2012,take the brain tissue specimens of steal blood area (in a distance5mm-lcm from deformity arteriolar),and the controlled trial are brain tissue specimens of8cases of cerebral trauma patients (4hours or less from injury to surgery) and2cases of huge arteriovenous which specimens is normal brain tissue to choose because of surgery decompression(more than5cm from the deformity arteriolar), make regular HE dyeing biopsy and transmission electron microscopy (sem).Conclusion:The tissue of the steal blood area arond the intracranial arteriovenous malformation (AVM) is characterized by a chronic hypoxia ischemic changes,the capillaries of the steal blood area around deformity arteriolar enlarge,endothelial cells of the blood vessels sparse,Foot process of the glial cells accidently insert into the blood vessel walls, these abnormal changes of the blood capillary and surrounding tissue are the conclusion of stealing blood by the AVM for a long time,and are the vicarious reaction chronic and hypoxia and ischemia phenomenons caused by the surrounding tissue. The edema of the cerebral, hemorrhage and the regeneration of the AVM may associate with the changes of the microvascular morphology of the steal blood area.