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Clinical And Neuroradiological Features Of Patients With Posterior Reversible Encephalopathy Syndrome

Posted on:2014-01-14Degree:MasterType:Thesis
Country:ChinaCandidate:Y Q ZhangFull Text:PDF
GTID:2254330425962878Subject:Neurology
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Posteriorreversibleencephalopathysyndrome(PRES)1996first independent encephalopathy syndrome in foreign countries reported[1], a cl inical-I mage sy ndrome, t he main clinical manifestations include vary ing degreesof headache, seizures, disturbance of consciousness, abnormal behavior ormental and visual disturbances, o ften accompanied by a sharp rise in bloodpressure. Reported occipital lesions, patients with isolated brainstem lesionsand cerebellum lesi ons rarely reported. Hypertension global prevalence rate,according to epidemiological survey, there is i ncreasing y ear by y ear, butthe awareness, control, co mpliance is l ow. Hypertension caused by a varietyof co mpli cations, which, particularly in the burden of stroke on the socialand famil y. Nearly10years of research suggests that hypertension of braintissue damage at an early stage if proper treatment can reverse recovery.Therefore, the acti ve control of high blood pressure, timely reversal ofhypertension on brain tissue damage, is of great significance. Contingent onthe clinical disease prone to misdiagnosis, with clinicians and radiologistson the back of the head reversible encephalopathy syndrome characteristicsrelated to lack of understanding. more co mmon in the back of the head; wasbilateral or unilateral, sy mmetry or non-sy mmetry of vasogenic brain Edema;cranial CT and MRI are the PRES common means of inspection,identification of vasogenic brain edema and cytotoxic brain edema can becombined with DWI and ADC maps. PRES frequency is reduced in accordance with lesions involving parts of the order: parietal, frontal lobe,temporal lobe, cerebellar hemispheres, the corpus callosum, thalamus andbrainstem. We collected six cases of isolated patients with brain stemlesions and cases of posterior inferior cerebellar artery deformity causedreversible posterior encephalopathy syndrome.6patients with isolatedbrainstem lesions have a previous history of hypertension, blood pressurewas significantly higher than the upper li mit of normal levels to visit.Posterior inferior cerebellar artery malformations induced reversibleposterior encephalopathy syndrome is the first case reported. PRES p atientsprognosis is usually good, timely and correct for the cause and dehydrationcontrol cerebral edema, symptomati c and supportive treat ment, the vastmajority of patients with clinical signs and sy mptoms may precederadiographic rapid i mprovement, consolidation therapy, allows i maginglesions basic or co mpletely disappeared, legacy lacunar infarctio n seen inso me pati ents. The Pande analysis PRES cause, extent of disease, brain stemand deep white mat ter involvement is low compared to other parts of thecortical area and cortical lesion reversibility reversible clinical relationship,eclampsia group compared to the reversibility of the hypertension group andchemotherapy group[70]. Delay ed diagnosis and treat ment can lead topermanent damage of the brain affect ed organizations[45,71], so t he PRESreversibility is not spontaneous, the clinicians and i mages doctors shouldi mprove understanding of the characteristics of PRES cases, t o avoidadverse ending. We now combine the cases co llected clinical data on itsclinical manifestations, etiology, pathological mechanisms, i magingfindings and diagnostic progress, further summary and discussion in orderto i mprove the diagnosis and treat ment of clinical work level.Purpose and Methods:Study by retrospective analy sis of patients with hypertension due to thePRES isolated brainstem l esions and patients with posterior inferiorcerebellar artery abnormalities PRES i solated brainstem l esions caused byhypertension, guide future clinical work. We have collected6patients, theiroriginal clinical data were retrospectively analyzed, and the recent development literature, in-depth to explore the etiology of PR ES, clinicalmanifestations and i maging features.Results:1.Caused by hypertension the PRES isolat ed brainstem lesio nsprognosis is usually good control of blood pressure is the key to thetreat ment.2. PR ES properly assess t he extent of disease and prognosis to a certainextent is the combination of DWI and ADC.3.The fig ure of ADC correct assess ment of disease extent andprognosis. ADC value of the prognosis of patients with a wealth ofinfor mati on to increase the ADC values of the lesions are reversible, ADCvalue lower lesions are often the last to lead to real cerebral infarction.4. PR ES needs the TOBS, encephalitis, SAH, venous thrombosis,demy elinating disease and other identification. Need and nervous sy stemvasculitis leukoencephalopathy, the hereditary cerebral artery disease andother neurological complicati ons of sy stemic disease identification.5. PR ES the cause of progress, the study found that to clear the corresponding lesions change caused by the differ ent causes, treat ment conduciveto disease recovery.6.PR ES will r ecur, chronic kidney disease polysulfone dialy zer membrane cellulose fil m can prevent the recurrence of recurrent PRES.
Keywords/Search Tags:Reversibleposteriorechoencephalograpthysyndrome, etiology, clinical manifestations, neuromata, treat ment, prognosis
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